Results 51 to 60 of about 69,446 (302)

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Exploring a curatorial turn in journalism [PDF]

open access: yes, 2015
Curation has moved from the ‘rarefied’ atmosphere of museums and exhibitions into journalism where new discourses and practices are proliferating. The changes have attracted academic attention such that journalism is now facing its own curatorial turn ...
Howarth, A
core  

Digital Curation [PDF]

open access: yesJournal of the Australian Library and Information Association, 2017
Book review:Digital Curation, (second edition), by Gillian Oliver, and Ross Harvey, Chicago, ALA, 2016, 224 pp., US$88.00, (soft cover), ISBN 978-0-8389-1385-7.
openaire   +3 more sources

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

A Letter to Krabstadt Education Center

open access: yesParse Journal, 2022
Gahee Park’s epistolary essay elaborates on the need to reframe the meaning of knowledge production in her curatorial practice. Musing upon Irit Rogoff’s ‘event of knowledge’, Park states that learning is a performative activity built through specific ...
Gahee Park
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Stewardship of the evolving scholarly record: from the invisible hand to conscious coordination [PDF]

open access: yes, 2015
The scholarly record is increasingly digital and networked, while at the same time expanding in both the volume and diversity of the material it contains.
Brian Lavoie, Constance Malpas
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Artists’ books in HE teaching and learning [PDF]

open access: yes, 2012
Learning resource, teaching collection, study collection, research collection or special collection: a historical collection of artists’ books like that at Chelsea College of Art & Design Library can (and probably, has) been used and referred to in all ...
Grandal Montero, Gustavo
core  

User Guided Design: Building Confidence in Engineering Data Publication [PDF]

open access: yes, 2016
Advances in imaging technology have generated large volumetric datasets in the field of petroleum engineering. To address the need to share this data, a multidisciplinary team developed the Digital Rocks Portal.
Esteva, Maria   +3 more
core   +1 more source

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