Results 61 to 70 of about 69,446 (302)

Data curation + process curation=data integration + science [PDF]

open access: yesBriefings in Bioinformatics, 2008
In bioinformatics, we are familiar with the idea of curated data as a prerequisite for data integration. We neglect, often to our cost, the curation and cataloguing of the processes that we use to integrate and analyse our data. Programmatic access to services, for data and processes, means that compositions of services can be made that represent the ...
Carole A. Goble   +4 more
openaire   +4 more sources

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

open access: yesMolecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic   +5 more
wiley   +1 more source

Enhanced Search for Educational Resources - A Perspective and a Prototype from ccLearn [PDF]

open access: yes, 2009
Users of search tools who seek educational materials on the Internet are typically presented with either a web-scale search (e.g., Google or Yahoo) or a specialized, site-specific tool.
Ahrash Bissell   +3 more
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Curating As a Brand Design Tool in Creative Organizations

open access: yesEconomia Creativa, 2014
Today the role of curating extends beyond the museum field: websites are curated, commercial firms establish functional roles entitled “curator”, and individuals in the creative economy use social media platforms to curate their lives and cultural ...
Natalie Nixon   +2 more
doaj   +1 more source

Redefining the performing arts archive [PDF]

open access: yes, 2009
This paper investigates representations of performance and the role of the archive. Notions of record and archive are critically investigated, raising questions about applying traditional archival definitions to the performing arts.
D Levy   +11 more
core   +1 more source

Comrades and curators

open access: yesJournal of Visual Literacy, 2019
This article shares the findings of a visual literacy project with museum curators and film educators. The research explores the mediation of social history and politics, the interplay of personal and professional curation and the role of reflexive visual literacy in understanding mediated identities.
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

The 'Inter-Disciplined' Exhibition - A Case Study

open access: yesMuseum & Society, 2020
This article contributes to the analysis and transparency of the practical processes of interdisciplinary exhibition-making. It identifies the academic discourse on interdisciplinarity as having the potential to provide a meaningful input to the ...
Henriette Pleiger
doaj   +1 more source

¡Viva el Blanton! [PDF]

open access: yes, 2006
Latin American ...
LLILAS Staff
core   +1 more source

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