Results 121 to 130 of about 213,267 (396)

Bioactive gliadin electrospinning loaded with Zataria multiflora Boiss essential oil: Improves antimicrobial activity and release modeling behavior

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 307-319, January 2023., 2023
Electrospinning‐assisted fabrication of gliadin was performed. The effects of processing parameters on morphology and properties were studied. The Zataria multiflora Boiss essential oil (ZMEO) was electro‐encapsulated in the nanofibers. Kinetic modeling on the ZMEO release from gliadin nanofibers was applied.
Zohreh Bahrami   +4 more
wiley   +1 more source

Curcumin upregulates transforming growth factor-β1, its receptors, and vascular endothelial growth factor expressions in an in vitro human gingival fibroblast wound healing model

open access: yesBMC Oral Health, 2021
Background Curcumin accelerates healing of oral wounds; however, the responsible mechanisms remain underexplored. Our hypothesis is curcumin regulates the expression of wound healing-related genes in human gingival fibroblasts (hGFs).
Auspreeya Rujirachotiwat   +1 more
doaj   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

open access: yesAdvanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han   +9 more
wiley   +1 more source

Preparation and characterization of an intelligent film based on fish gelatin and Coleus scutellarioides anthocyanin to monitor the freshness of rainbow trout fish fillet

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 379-389, January 2023., 2023
A pH‐sensitive indicator based on fish gelatin and Coleus scutellarioides anthocyanin extract (CSAE) was prepared and characterized. There was also a significant relationship between the TVB‐N content of fish fillets and the a* index of the film during the 16 hours storage period so that with the increase of TVB‐N values of the fillets during the ...
Fahimeh Hematian   +3 more
wiley   +1 more source

Antidiabetic effect of Tibetan medicine Tang-Kang-Fu-San on high-fat diet and streptozotocin-induced type 2 diabetic rats [PDF]

open access: yes, 2017
The aim of this study was to investigate the antidiabetic effects of a Tibetan medicine, Tang-Kang-Fu-San (TKFS), on experimental type 2 diabetes mellitus (T2DM) rats and to explore its underlying mechanisms.
Duan, Bailu   +8 more
core   +3 more sources

Metal–Organic Frameworks: Unlocking New Frontiers in Cardiovascular Diagnosis and Therapy

open access: yesAdvanced Science, EarlyView.
Metal–organic frameworks (MOFs), are composed of metal ions and bridging organic ligands, are recognized as an excellent platform for host‐gust chemistry. Its rich structural composition, modifiable sites, and multilevel pore distribution can provide delivery and release of signaling molecules, probes, and therapeutic drugs, which exhibit great medical
Qilu Wu   +6 more
wiley   +1 more source

Pyrus ussuriensis Maxim 70% ethanol eluted fraction ameliorates inflammation and oxidative stress in LPS‐induced inflammation in vitro and in vivo

open access: yesFood Science &Nutrition, Volume 11, Issue 1, Page 458-469, January 2023., 2023
In this work, we demonstrated that PUM70 specifically suppressed LPS‐mediated inflammatory responses. Notably, PUM70 treatment inhibited LPS‐induced lung damage, pro‐inflammatory cytokine production, and reduced macrophage infiltration in the lungs. Mechanistically, PUM70 suppressed LPS‐induced inflammation and oxidative stress via the Nrf2/HO‐1 and ...
Fei Peng, Xin Ren, Bin Du, Yuedong Yang
wiley   +1 more source

Niosomes in cancer treatment: A focus on curcumin encapsulation

open access: yesHeliyon, 2023
Curcumin is widely used as a therapeutic drug for cancer treatment. However, its limited absorption and rapid excretion are the major therapeutic limitations to its clinical use.
Thaaranni Bashkeran   +6 more
doaj  

Chloroquine supplementation increases the cytotoxic effect of curcumin against Her2/neu overexpressing breast cancer cells in vitro and in vivo in nude mice while counteracts it in immune competent mice [PDF]

open access: yes, 2017
Autophagy is usually a pro-survival mechanism in cancer cells, especially in the course of chemotherapy, thus autophagy inhibition may enhance the chemotherapy-mediated anti-cancer effect.
Bei, R.   +10 more
core   +1 more source

COPS5 Triggers Ferroptosis Defense by Stabilizing MK2 in Hepatocellular Carcinoma

open access: yesAdvanced Science, EarlyView.
COPS5, which is overexpressed in HCC in an amplification‐ and ATF4‐dependent manner, stabilizes MK2 through deubiquitination and, in turn, induces HSPB1 activation, protecting HCC cells from ferroptosis and thus promoting sorafenib resistance and tumor progression. Abstract Sorafenib, which is proven to serve as a potent ferroptosis inducer, is used as
Ai‐Ling Luo   +15 more
wiley   +1 more source

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