Results 81 to 90 of about 106,368 (305)

Textural Properties of Carbopol® Gel with Curcumin and Curcumin–HPβCD Inclusion Complex and Biological Activities

open access: yesGels
The aim of this study was to prepare curcumin/2-hydroxypropyl-β-cyclodextrin (HPβCD) inclusion complex, evaluate the antioxidant and antimicrobial activities of curcumin and curcumin in inclusion complex, as well as to examine the effect of curcumin and ...
Maja Urošević   +7 more
doaj   +1 more source

Stabilization of Curcumin by Complexation with Divalent Cations in Glycerol/Water System

open access: yesBioinorganic Chemistry and Applications, 2010
The purpose of present study was to stabilize curcumin food pigment by its complexation with divalent ions like (Zn2+,Cu2+,Mg2+,Se2+), in “green media” and evaluate its stability in vitro compared to curcumin alone.
Bachar Zebib   +2 more
doaj   +1 more source

Multiple antidepressant potential modes of action of curcumin: A review of its anti-inflammatory, monoaminergic, antioxidant, immune-modulating and neuroprotective effects

open access: yes, 2012
Curcumin is the principal curcuminoid of the popular Indian spice turmeric and has attracted increasing attention for the treatment of a range of conditions.
Hood, S.D.   +5 more
core  

Curcumin-induced mitotic arrest is characterized by spindle abnormalities, defects in chromosomal congression and DNA damage. [PDF]

open access: yes, 2013
The chemopreventive agent curcumin has anti-proliferative effects in many tumour types, but characterization of cell cycle arrest, particularly with physiologically relevant concentrations, is still incomplete.
Manson, Margaret M.   +7 more
core   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

open access: yesAdvanced NanoBiomed Research, EarlyView.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

Acetylation: a critical factor in maintaining intestinal inflammation?

open access: yes, 2010
PhDIn inflammatory bowel disease (IBD), both chronic pro-inflammatory pathways and failure of anti-inflammatory (healing) mechanisms sustain disease. The two major anti-inflammatory gut cytokines are transforming growth factor (TGF)-β and interleukin (IL)
Epstein, Jenny
core  

Novel curcumin analogs to overcome EGFR-TKI lung adenocarcinoma drug resistance and reduce EGFR-TKI-induced GI adverse effects

open access: yes, 2017
Curcumin (1) down-regulates the expression as well as phosphorylation of epidermal growth factor receptor (EGFR) in lung adenocarcinoma cells expressing gefitinib-resistant EGFR.
Wada, Koji;Lee, Jen-Yi;Hung, Hsin-Yi;Shi, Qian;Lin, Li;Zhao, Yu;Goto, Masuo;Yang, Pan-Chyr;Kuo, Sheng-Chu;Chen, Hui-Wen;Lee, Kuo-Hsiung   +1 more
core   +1 more source

Spatial Cell Death and Oxidative Stress Dynamics in Gas Plasma‐Treated Tumor Tissues

open access: yesAdvanced NanoBiomed Research, EarlyView.
Schematic representation of the four experimental models to study tissue penetration and oxidation. Four tissue models were used. Human pancreatic cancer cells were grown on the chorioallantois membrane of chicken embryos and gas plasma‐treated in ovo, murine colorectal tumor tissue was gas plasma‐exposed ex vivo, murine squamous cell carcinoma cells ...
Anke Schmidt   +4 more
wiley   +1 more source

Scale-Up Synthesis and In Vivo Anti-Tumor Activity of Curcumin Diethyl Disuccinate, an Ester Prodrug of Curcumin, in HepG2-Xenograft Mice

open access: yesPharmaceutics, 2019
Previously, we synthesized curcumin and a succinate ester prodrug of curcumin namely curcumin diethyl disuccinate (CurDD) in the lab scale, which yielded hundred milligrams to few grams of the compounds.
Chawanphat Muangnoi   +7 more
doaj   +1 more source

Curcumin-Containing Diet Inhibits Diethylnitrosamine-Induced Murine Hepatocarcinogenesis

open access: yes, 2009
Curcumin has been widely used as a spice and coloring agent in foods. Recently, curcumin was found to possess chemopreventive effects against skin cancer, forestomach cancer, colon cancer and oral cancer in mice.
CHUANG, SHUANG-EN;KUO, MIN-LIANG;HSU, CHIH-HUNG;CHEN, CHI-LONG;LIN, JEN-KUN;LAI, GI-MING;HSIEH, CHANG-YAO;CHENG, ANN-LII   +1 more
core  

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