Results 61 to 70 of about 106,911 (306)

Chemoproteomic Identification of AKT2 as a Paclitaxel‐Binding Protein via C─C Bond‐Linked Probe PTX‐4 in Paclitaxel‐Resistant Breast Cancer

open access: yesAdvanced Science, EarlyView.
ABSTRACT Breast cancer remains one of the most prevalent malignancies among women, and taxane‐based chemotherapies such as paclitaxel and docetaxel are central to standard treatment regimens. However, drug resistance in breast cancer limits therapeutic efficacy and contributes to recurrence and metastasis.
Kai Wang   +7 more
wiley   +1 more source

Synergistic Antitumor Effect of Curcumin and Dinitrosyl Iron Complexes for Against Melanoma Cells [PDF]

open access: yes, 2010
[[abstract]]The aim of this study was to examine whether combining curcumin, a chemoprevention agent, and dinitrosyl iron complexes (DNICs) would have a synergistic cytotoxic effect on mouse melanoma B16-F10 cells in vitro. Three synthesized DNICs-[PPN] [
Wen YD; Ho YL; Shiau RJ; Yeh JK; Wu JU; Wang WL; Chiou SJ.
core  

Nghiên cứu phức hợp của curcumin với hydroxypropyl-β-cyclodextrin có sinh khả dụng cao

open access: yesTạp chí Khoa học Đại học Cần Thơ, 2019
Hoạt tính sinh học của curcumin trong nghệ rất được quan tâm bởi giá trị hữu ích của nó trong thực phẩm, mỹ phẩm cũng như trong điều trị bệnh ở người. Tuy nhiên, tiềm năng sinh học của curcumin vẫn chưa được khai thác hết do độ hòa tan thấp, dẫn đến sự ...
Lưu Thái Danh   +5 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Anionic Surfactant Based Topical Curcumin Nanosuspension: Fabrication, Characterization and Evaluation

open access: yesNano Biomedicine and Engineering, 2013
Curcumin, a hydrophobic polyphenol isolated from dried rhizomes of turmeric exhibits diverse pharmacological activities including anti-bacterial. However, the clinical usefulness of curcumin was limited mainly due to low aqueous solubility and stability.
Moorthi Chidambaram   +3 more
doaj   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

open access: yesAdvanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang   +3 more
wiley   +1 more source

Stability of Curcumin in Buffer Solutions and Characterization of Its Degradation Products [PDF]

open access: yes, 2008
The degradation kinetics of curcumin under various pH conditions and the stability of curcumin in physiological matrices were investigated. When curcumin was incubated in 0 .1 M phosphate buffer and serum-free medium, pH 7.2 at 37 degrees C, about 90 ...
WANG, YING-JAN;PAN, MIN-HSIUNG;CHENG, ANN-LII;LIN, LIANG-IN;HO, YUAN-SOON;HSIEH, CHANG-YAO;LIN, JEN-KUN   +1 more
core  

Curcumin suppresses RANKL-induced osteoclast precursor autophagy in osteoclastogenesis by inhibiting RANK signaling and downstream JNK-BCL2-Beclin1 pathway

open access: yesBiomedical Journal
Background: Curcumin ameliorates bone loss by inhibiting osteoclastogenesis. Curcumin inhibits RANKL-promoted autophagy in osteoclast precursors (OCPs), which mediates its anti-osteoclastogenic effect.
Dianshan Ke   +7 more
doaj   +1 more source

Essential turmeric oils enhance anti-inflammatory efficacy of curcumin in dextran sulfate sodium-induced colitis

open access: yesScientific Reports, 2017
Turmeric has been used as a medicinal herb for thousands of years for treatment of various disorders. Although curcumin is the most studied active constituents of turmeric, accumulating evidence suggests that other components of turmeric have additional ...
Shusuke Toden   +3 more
doaj   +1 more source

Anti-inflammatory effect of different curcumin preparations on adjuvant-induced arthritis in rats

open access: yesBMC Complementary Medicine and Therapies, 2021
Background Curcumin, a natural polyphenolic substance, has been known for more than two millennia as having strong anti-inflammatory activity towards multiple ailments, including arthritis.
Ieva Rinkunaite   +4 more
doaj   +1 more source

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