Results 61 to 70 of about 106,368 (305)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

A Lipid‐Conjugation Strategy for Intracellular Reactive Oxygen Species Control in Hepatic Cells

Angewandte Chemie, EarlyView.
A lipid conjugation strategy anchors a manganese Salen complex within phospholipid membranes, yielding stable, catalytically active liposomes. These lipid–metal assemblies efficiently degrade reactive oxygen species (ROS) and enable intracellular redox control in steatotic HepaRG cells, offering a precise route to biomimetic antioxidant design ...
Olav Vestrheim, Huichao Zhao, Anders Bodholt Nielsen, Nino Wili, Niels Chr. Nielsen, Joseph A. Lyons, Rajeshwar Prosad Mookerjee, Brigitte Städler   +7 more
wiley   +2 more sources

Microglia‐Targeted Biomimetic Tetrahedral Framework Nucleic Acid Nanovesicles for Synergistic Treatment of Sepsis‐Associated Encephalopathy

Advanced Science, EarlyView.
Sepsis‐associated encephalopathy (SAE) lacks effective therapies. We developed ME@FDsi, a biomimetic nanodrug using a tetrahedral framework nucleic acid to deliver disulfiram and siTNFα. It crosses the blood‐brain barrier, targets M1 microglia, inhibits pyroptosis and inflammation, and scavenges ROS.
Huimin Shi, Qiuxia Gao, Wenying Wang, Bin Li, Yukun Chen, Zhijun Yao, Yujie Li, Junrui Li, Na Li, Gong Gu, Zhimin Hou, Mengyuan Yang, Ruilin Zhang, Hongju Yang, Yuhui Liao, Hongyi Lei   +15 more
wiley   +1 more source

Essential turmeric oils enhance anti-inflammatory efficacy of curcumin in dextran sulfate sodium-induced colitis

Scientific Reports, 2017
Turmeric has been used as a medicinal herb for thousands of years for treatment of various disorders. Although curcumin is the most studied active constituents of turmeric, accumulating evidence suggests that other components of turmeric have additional ...
Shusuke Toden, Arianne L. Theiss, Xuan Wang, Ajay Goel   +3 more
doaj   +1 more source

Anionic Surfactant Based Topical Curcumin Nanosuspension: Fabrication, Characterization and Evaluation

Nano Biomedicine and Engineering, 2013
Curcumin, a hydrophobic polyphenol isolated from dried rhizomes of turmeric exhibits diverse pharmacological activities including anti-bacterial. However, the clinical usefulness of curcumin was limited mainly due to low aqueous solubility and stability.
Moorthi Chidambaram, Senthilkumar Chinnamaruthu, Mohan Sellappan, Kathiresan Krishnasamy   +3 more
doaj   +1 more source

Spontaneous Non‐Catalyzed Molecular Reactions and Interactions in the Human Body: Biomedical Implications

Advanced Science, EarlyView.
ABSTRACT The human body functions as a natural reactor for a vast network of chemical and biological reactions and physical interactions among small molecules, proteins, cells, and numerous other components. These reactions/interactions are essential for maintaining normal physiological functions.
Yuhao Cai, Chao Zhao
wiley   +1 more source

Is Curcumin an Antidote for Civilization Diseases? A Literature Review

Quality in Sport
Introduction and purpose: Curcumin is the main natural lipophilic polyphenol obtained from Curcuma longa L. Its anti-inflammatory, anti-cancerous, anti-obesity, antioxidant, and lipid-lowering effects have attracted scientists' attention.
Adrianna Madej, Adrian Suława, Oskar Targoński, Marta Targońska, Julia Furgalska-Kudła , Sebastian Fedorowicz, Aneta Basiak, Aleksander Ptasiński , Rafał Niekurzak, Agnieszka Buczek   +9 more
doaj   +1 more source

Interação entre a administração crônica de curcumina e de manganês sobre parâmetros comportamentais e neuroquímicos em camundongos [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2013O manganês (Mn) é um dos metais mais abundantes da crosta terrestre, sendo encontrado em rochas,
Schmitz, Ariana Ern
core  

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

In vitro evaluation of antioxidant and neuroprotective effects of curcumin loaded in Pluronic micelles

Biotechnology & Biotechnological Equipment, 2016
Curcumin is a polyphenolic substance with attractive pharmacological activities (e.g. antioxidant, anti-inflammatory, anticancer). Incorporation of curcumin in polymeric micelles could overcome the problems associated with its instability and low aqueous
Cvetelina Gorinova, Denitsa Aluani, Yordan Yordanov, Magdalena Kondeva-Burdina, Virginia Tzankova, Cvetelina Popova, Krassimira Yoncheva   +6 more
doaj   +1 more source