Results 61 to 70 of about 121,413 (201)

Curcumin-Poly(sodium 4‑styrenesulfonate) Conjugates as Potent Zika Virus Entry Inhibitors

Curcumin, a natural product with recognized antiviral properties, is limited in its application largely due to its poor solubility. This study presents the synthesis of water-soluble curcumin-poly(sodium 4-styrenesulfonate) (Cur-PSSNan) covalent ...
Krzysztof Pyrć (4497517), Aneta Medaj (17857780), Paweł Botwina (6524093), Krzysztof Szczubiałka (1815352), Magdalena Obłoza (7471376), Artur Szczepański (17857777), Piotr Bonarek (3922337), Aleksandra Milewska (2818312), Maria Nowakowska (703338)   +8 more
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Exploring the potential of curcumin-loaded PLGA nanoparticles for angiogenesis and antioxidant proficiency in zebrafish embryo (Danio rerio)

Future Journal of Pharmaceutical Sciences
Background Curcumin is an age old traditional medicine. Although curcumin has several advantages, its water solubility and bioavailability limit its use as a natural therapeutic agent.
Achinta Singha, Mave Harshitha, Krithika Kalladka, Gunimala Chakraborty, Biswajit Maiti, Akshath Uchangi Satyaprasad, Anirban Chakraborty, Samir Kumar Sil   +7 more
doaj   +1 more source

Curcumin-Containing Diet Inhibits Diethylnitrosamine-Induced Murine Hepatocarcinogenesis

, 2009
Curcumin has been widely used as a spice and coloring agent in foods. Recently, curcumin was found to possess chemopreventive effects against skin cancer, forestomach cancer, colon cancer and oral cancer in mice.
CHUANG, SHUANG-EN;KUO, MIN-LIANG;HSU, CHIH-HUNG;CHEN, CHI-LONG;LIN, JEN-KUN;LAI, GI-MING;HSIEH, CHANG-YAO;CHENG, ANN-LII, 莊雙恩;郭明良;徐志宏;陳志榮;林仁混;賴基銘;謝長堯;鄭安理   +1 more
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Curcumin inhibits the replication of enterovirus 71 in vitro

Acta Pharmaceutica Sinica B, 2014
Human enterovirus 71 (EV71) is the main causative pathogen of hand, foot, and mouth disease (HFMD) in children. The epidemic of HFMD has been a public health problem in Asia-Pacific region for decades, and no vaccine and effective antiviral medicine are ...
Ying Qin, Lexun Lin, Yang Chen, Shuo Wu, Xiaoning Si, Heng Wu, Xia Zhai, Yan Wang, Lei Tong, Bo Pan, Xiaoyan Zhong, Tianying Wang, Wenran Zhao, Zhaohua Zhong   +13 more
doaj   +1 more source

Suppression of Protein Kinase C and Nuclear Oncogene Expression as Possible Action Mechanisms of Cancer Chemoprevention by Curcumin

, 2009
Curcumin (diferuloylmethane) is a major naturally-occurring polyphenol of Curcuma species, which is commonly used as a yellow coloring and flavoring agent in foods. Curcumin has shown anti-carcinogenic activity in animal models.
林仁混, LIN, JEN-KUN
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Curcumin inhibits proliferation, migration, invasion and promotes apoptosis of retinoblastoma cell lines through modulation of miR-99a and JAK/STAT pathway

BMC Cancer, 2018
Background Curcumin, a primary active ingredient extracted from the Curcuma longa, has been recently identified as a potential anti-tumor agent in multiple kinds of cancers.
Yaping Li, Weixuan Sun, Ning Han, Ying Zou, Dexin Yin   +4 more
doaj   +1 more source

Interação entre a administração crônica de curcumina e de manganês sobre parâmetros comportamentais e neuroquímicos em camundongos [PDF]

, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Neurociências, Florianópolis, 2013O manganês (Mn) é um dos metais mais abundantes da crosta terrestre, sendo encontrado em rochas,
Schmitz, Ariana Ern
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Antifibrotic Activity and In Ovo Toxicity Study of Liver-Targeted Curcumin-Gold Nanoparticle

Scientia Pharmaceutica, 2018
Conjugation of curcumin and gold with green chemistry is an approach to improve the effectiveness of curcumin as anti-fibrosis. In this work, curcumin and gold were conjugated to deliver curcumin to the liver.
Amirah Adlia, Ilham Tomagola, Sophi Damayanti, Ardyanto Mulya, Heni Rachmawati   +4 more
doaj   +1 more source

Curcumin-induced mitotic arrest is characterized by spindle abnormalities, defects in chromosomal congression and DNA damage.

, 2013
The chemopreventive agent curcumin has anti-proliferative effects in many tumour types, but characterization of cell cycle arrest, particularly with physiologically relevant concentrations, is still incomplete.
LM Blakemore (7632308), R Cordell (7632314), MM Manson (7632317), C Boes (7632311)   +3 more
core   +2 more sources

Synergistic Antitumor Effect of Curcumin and Dinitrosyl Iron Complexes for Against Melanoma Cells

, 2010
[[abstract]]The aim of this study was to examine whether combining curcumin, a chemoprevention agent, and dinitrosyl iron complexes (DNICs) would have a synergistic cytotoxic effect on mouse melanoma B16-F10 cells in vitro. Three synthesized DNICs-[PPN] [
Wen YD; Ho YL; Shiau RJ; Yeh JK; Wu JU; Wang WL; Chiou SJ.
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