Drug-Drug/Drug-Excipient Compatibility Studies on Curcumin using Non-Thermal Methods
Advanced Pharmaceutical Bulletin, 2014 Purpose: Curcumin is a hydrophobic polyphenol isolated from dried rhizome of turmeric. Clinical usefulness of curcumin in the treatment of cancer is limited due to poor aqueous solubility, hydrolytic degradation, metabolism, and poor oral bioavailability.
Moorthi Chidambaram +1 more
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Curcumin Suppresses the Colon Cancer Proliferation by Inhibiting Wnt/β-Catenin Pathways via miR-130a
Frontiers in Pharmacology, 2017 Curcumin exhibits anti-tumor effects in several cancers, including colorectal carcinoma (CRC), but the detailed mechanisms are still unclear. Here we studied the mechanisms underlying the anti-tumor effect of curcumin in colon cancer cells.
Huiqiang Dou +7 more
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Synthesis of Metal–Curcumin Complex Compounds (M = Na⁺, Mg²⁺, Cu²⁺)
Jurnal Kimia Sains dan Aplikasi, 2020 Curcumin complex compound, MLn (L = curcumin; M = Na+, Mg2+, Cu2+) has been synthesized from the reaction between curcumin and metal precursors (NaCl, MgSO4.7H2O, CuCl2.2H2O) in ethanol under reflux conditions.
Peni Peni +2 more
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Multiple antidepressant potential modes of action of curcumin: A review of its anti-inflammatory, monoaminergic, antioxidant, immune-modulating and neuroprotective effects [PDF]
, 2012 Curcumin is the principal curcuminoid of the popular Indian spice turmeric and has attracted increasing attention for the treatment of a range of conditions.
Hood, S.D. +5 more
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Lethal Effect of Various Derivatives of Curcumin on Trichomonas vaginalis in vitro
Iranian South Medical Journal, 2018 Background: Trichomoniasis is a common urogenital disease in the world. The first line of treatment for Trichomoniasis is metronidazole. Drug resistance and side effects of metronidazole urge researchers to seek new medications.
MoradAli Fouladvand +4 more
doaj
Curcumin-Loaded Blood-Stable Polymeric Micelles for Enhancing Therapeutic Effect on Erythroleukemia
, 2017 Curcumin has high potential in suppressing many types of cancer and overcoming multidrug resistance in a multifaceted manner by targeting diverse molecular targets.
Xin Teng (384533) +7 more
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Nghiên cứu phức hợp của curcumin với hydroxypropyl-β-cyclodextrin có sinh khả dụng cao
Tạp chí Khoa học Đại học Cần Thơ, 2019 Hoạt tính sinh học của curcumin trong nghệ rất được quan tâm bởi giá trị hữu ích của nó trong thực phẩm, mỹ phẩm cũng như trong điều trị bệnh ở người. Tuy nhiên, tiềm năng sinh học của curcumin vẫn chưa được khai thác hết do độ hòa tan thấp, dẫn đến sự ...
Lưu Thái Danh +5 more
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Nano Biomedicine and Engineering, 2013 Curcumin, a hydrophobic polyphenol isolated from dried rhizomes of turmeric exhibits diverse pharmacological activities including anti-bacterial. However, the clinical usefulness of curcumin was limited mainly due to low aqueous solubility and stability.
Moorthi Chidambaram +3 more
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Anti-inflammatory effect of different curcumin preparations on adjuvant-induced arthritis in rats
BMC Complementary Medicine and Therapies, 2021 Background Curcumin, a natural polyphenolic substance, has been known for more than two millennia as having strong anti-inflammatory activity towards multiple ailments, including arthritis.
Ieva Rinkunaite +4 more
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Scientific Reports, 2017 Turmeric has been used as a medicinal herb for thousands of years for treatment of various disorders. Although curcumin is the most studied active constituents of turmeric, accumulating evidence suggests that other components of turmeric have additional ...
Shusuke Toden +3 more
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