Results 31 to 40 of about 106,368 (305)

Effects of curcumin intake and aerobic exercise training on arterial compliance in postmenopausal women

Artery Research, 2012
Background: Reduction in arterial compliance with aging increases the risk of cardiovascular disease. Lifestyle modification, particularly aerobic exercise and dietary modification, has a favorable effect on vascular aging. Curcumin, a major component of
Nobuhiko Akazawa, Youngju Choi, Asako Miyaki, Yoko Tanabe, Jun Sugawara, Ryuichi Ajisaka, Seiji Maeda   +6 more
doaj   +1 more source

Curcumin upregulates transforming growth factor-β1, its receptors, and vascular endothelial growth factor expressions in an in vitro human gingival fibroblast wound healing model

BMC Oral Health, 2021
Background Curcumin accelerates healing of oral wounds; however, the responsible mechanisms remain underexplored. Our hypothesis is curcumin regulates the expression of wound healing-related genes in human gingival fibroblasts (hGFs).
Auspreeya Rujirachotiwat, Supaporn Suttamanatwong   +1 more
doaj   +1 more source

Evaluation of Lethal Effect of Curcumin and its Derivatives Against Leishmania Major In Vitro

Iranian South Medical Journal, 2020
Background: Leishmania major is transmitted by sandflies of the genus Phobotomus and causes cutaneous lesions in humans. Curcumin is made from turmeric and various derivatives is derived from it.
MoradAli Fouladvand, Solyman Khorami, Behroz Naeimi, Sohila Fotouhi, Khosro Mohammadi   +4 more
doaj  

Curcumin Reverse Methicillin Resistance in Staphylococcus aureus

Molecules, 2014
Curcumin, a natural polyphenolic flavonoid extracted from the rhizome of Curcuma longa L., was shown to possess superior potency to resensitize methicillin-resistant Staphylococcus aureus (MRSA) to antibiotics. Previous studies have shown the synergistic
Su-Hyun Mun, Sung-Bae Kim, Ryong Kong, Jang-Gi Choi, Youn-Chul Kim, Dong-Won Shin, Ok-Hwa Kang, Dong-Yeul Kwon   +7 more
doaj   +1 more source

Characterization of human bone marrow derived mesenchymal stem cells as a model for in vitro adipocytes studies [PDF]

, 2013
Overweight and obesity are major problems of public health in many countries worldwide. Overweight can cause severe diseases such as type II diabetes mellitus, hypertension, stroke, heart failure and several types of cancer.
Hirzel, Estelle
core   +1 more source

The protective effects of curcumin and curmumin nanomicelle against cirrhotic cardiomyopathy in bile duct-ligated rats [PDF]

Nanomedicine Journal, 2020
Objective(s): Cirrhotic cardiomyopathy refers to cardiac muscle dysfunction caused by liver cirrhosis. Seemingly, free radicals and inflammatory factors play a critical role in the pathophysiology of cardiomyopathy.
Mohammad Sheibani, Ahmad Reza Dehpour, Sadaf Nezamoleslami, Seyedeh Elaheh Mousavi, Mahmoud Reza Jafari, Seyed Mahdi Rezayat Sorkhabadi   +5 more
doaj   +1 more source

Visible light is a better co-inducer of apoptosis for curcumin-treated human melanoma cells than UVA

, 2013
Curcumin attracts worldwide scientific interest due to its anti-proliferative and apoptosis inducing effects on different tumor cells at concentrations ranging from 10 to 150 µM (3.7–55 µg/ml).
Kerstin Goerg, Hofmann, Matthias, Roland Kaufmann, Goerg, Kerstin, Stefan Kippenberger, Jadranka Dobra, Kippenberger, Stefan, August Bernd, Buss, Stephan, Stephanie Hoffmann, Matthias Hofmann, Hoffmann, Stephanie, Stephan Buss, Dobra, Jadranka, Bernd, August, Kaufmann, Roland   +15 more
core   +1 more source

Integrated molecular and ADME-toxicity profiling identifies PGV-5 and HGV-5 as potential agents to counteract multidrug-resistant (MDR) cancer

Scientific Reports
Curcumin, a pharmacological agent found in turmeric’s rhizome, has been studied for its various therapeutic properties. However, its clinical development is hindered by its instability and low solubility in water, resulting in inadequate oral ...
Ritmaleni, Rosalina Diani Prima Anargya, Najla Alivia, Prajona Marbun, Retno Murwanti, Ranti Kamila Habibie   +5 more
doaj   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

Drug-Drug/Drug-Excipient Compatibility Studies on Curcumin using Non-Thermal Methods

Advanced Pharmaceutical Bulletin, 2014
Purpose: Curcumin is a hydrophobic polyphenol isolated from dried rhizome of turmeric. Clinical usefulness of curcumin in the treatment of cancer is limited due to poor aqueous solubility, hydrolytic degradation, metabolism, and poor oral bioavailability.
Moorthi Chidambaram, Kathiresan Krishnasamy   +1 more
doaj   +1 more source