Bioinformatics study and cytotoxicity of several curcumin analogues in ovarian cancer
Current Research in ToxicologyOvarian cancer ranks as Indonesia’s third-leading cause of cancer-related death, emphasising the need for innovative treatments. This study combined bioinformatics, molecular docking, and experimental assays to tackle this challenge.
Retno Murwanti +5 more
doaj +1 more source
Curcumin-Loaded Blood-Stable Polymeric Micelles for Enhancing Therapeutic Effect on Erythroleukemia [PDF]
, 2017 Curcumin has high potential in suppressing many types of cancer and overcoming multidrug resistance in a multifaceted manner by targeting diverse molecular targets.
Xin Teng (384533) +7 more
core +1 more source
Curcumin-Encapsulated Fusion Protein-Based Nanocarrier Demonstrated Highly Efficient Epidermal Growth Factor Receptor-Targeted Treatment of Colorectal Cancer [PDF]
, 2022 Curcumin, a polyphenol derived from turmeric, has multiple biological functions, such as anti-inflammatory, antioxidant, antibacterial and, above all, antitumor activity.
Bo Wang (86769) +8 more
core +1 more source
Evaluation of Lethal Effect of Curcumin and its Derivatives Against Leishmania Major In Vitro
Iranian South Medical Journal, 2020 Background: Leishmania major is transmitted by sandflies of the genus Phobotomus and causes cutaneous lesions in humans. Curcumin is made from turmeric and various derivatives is derived from it.
MoradAli Fouladvand +4 more
doaj
Curcumin Reverse Methicillin Resistance in Staphylococcus aureus
Molecules, 2014 Curcumin, a natural polyphenolic flavonoid extracted from the rhizome of Curcuma longa L., was shown to possess superior potency to resensitize methicillin-resistant Staphylococcus aureus (MRSA) to antibiotics. Previous studies have shown the synergistic
Su-Hyun Mun +7 more
doaj +1 more source
BMC Oral Health, 2021 Background Curcumin accelerates healing of oral wounds; however, the responsible mechanisms remain underexplored. Our hypothesis is curcumin regulates the expression of wound healing-related genes in human gingival fibroblasts (hGFs).
Auspreeya Rujirachotiwat +1 more
doaj +1 more source
Characterization of human bone marrow derived mesenchymal stem cells as a model for in vitro adipocytes studies [PDF]
, 2013 Overweight and obesity are major problems of public health in many countries worldwide. Overweight can cause severe diseases such as type II diabetes mellitus, hypertension, stroke, heart failure and several types of cancer.
Hirzel, Estelle
core +1 more source
The protective effects of curcumin and curmumin nanomicelle against cirrhotic cardiomyopathy in bile duct-ligated rats [PDF]
Nanomedicine Journal, 2020 Objective(s): Cirrhotic cardiomyopathy refers to cardiac muscle dysfunction caused by liver cirrhosis. Seemingly, free radicals and inflammatory factors play a critical role in the pathophysiology of cardiomyopathy.
Mohammad Sheibani +5 more
doaj +1 more source
Scientific ReportsCurcumin, a pharmacological agent found in turmeric’s rhizome, has been studied for its various therapeutic properties. However, its clinical development is hindered by its instability and low solubility in water, resulting in inadequate oral ...
Ritmaleni +5 more
doaj +1 more source