Curcumin-loaded apotransferrin nanoparticles provide efficient cellular uptake and effectively inhibit HIV-1 replication in vitro. [PDF]
PLoS ONE, 2011 Curcumin (diferuloylmethane) shows significant activity across a wide spectrum of conditions, but its usefulness is rather limited because of its low bioavailability.
Upendhar Gandapu +4 more
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Comparison of Inhibitory Effect of Curcumin Nanoparticles and Free Curcumin in Human Telomerase Reverse Transcriptase Gene Expression in Breast Cancer [PDF]
Advanced Pharmaceutical Bulletin, 2013 Purpose: Telomerase is expressed in most cancers, including breast cancer. Curcumin, a polyphenolic compound that obtained from the herb of Curcuma longa, has many anticancer effects. But, its effect is low due to poor water solubility.
Nosratollah Zarghami +2 more
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Molecules, 2016 Nowadays, there are some molecules that have shown over the years a high capacity to act against relevant pathologies such as cardiovascular disease, neurodegenerative disorders or cancer. This article provides a brief review about the origin, bioavailability and new research on curcumin and synthetized derivatives.
Mario Pulido-Moran +3 more
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Current Drug Targets, 2011 Curcumin (diferuloylmethane), an orange-yellow component of turmeric or curry powder, is a polyphenol natural product isolated from the rhizome of the plant Curcuma longa. For centuries, curcumin has been used in some medicinal preparation or used as a food-coloring agent.
Hongyu, Zhou +2 more
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Curcumin and butyrate induce fibroblast senescence without the emergence of fibrosis biomarkers
Aspects of Molecular Medicine, 2023 Background: Small molecules have emerged as valuable tools to modulate cellular homeostasis and the changes associated with aging. In particular, the phytochemical curcumin elicits cytoprotective effects that promote human health and longevity. The short-
Siwei Chu +5 more
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Antimicrobial Activity of Curcumin and Deuterated Curcumin
Journal of Natural Remedies, 2022 Deuterium (D) and hydrogen (H) are bioisosteres because they are similar in size and shape with alike physiochemical properties and hence expect similar biological activity. The purpose of replacing H with D is to extend the time the active drug species spends in plasma, resulting in increased effectiveness and/or the avoidance of unwanted side effects.
G. V. Anjana, M. K. Kathiravan
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Processing Stabilisation of PE with a Natural Antioxidant, Curcumin [PDF]
, 2013 The potential use of natural antioxidants for polyolefin stabilisation came into the centre of attention because of some doubts about the effects of the reaction products of synthetic phenolic antioxidants on human health.
Tátraaljai, Dóra +4 more
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The chemopreventive polyphenol Curcumin prevents hematogenous breast cancer metastases in immunodeficient mice [PDF]
, 2007 Dissemination of metastatic cells probably occurs long before diagnosis of the primary tumor. Metastasis during early phases of carcinogenesis in high risk patients is therefore a potential prevention target.
Iancu, Cristina M. +9 more
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Therapeutic Potential of Curcumin as an Antimycobacterial Agent
Biomolecules, 2021 Curcumin is the principal curcuminoid obtained from the plant Curcuma longa and has been extensively studied for its biological and chemical properties.
Nilakshi Barua, Alak Kumar Buragohain
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Development, Characterization and Pharmacokinetic Profile of Chitosan-Sodium Tripolyphosphate Nanoparticles Based Drug Delivery Systems for Curcumin [PDF]
Advanced Pharmaceutical Bulletin, 2021 Purpose: This study aimed to provide the method of preparation, characterization of curcumin-loaded chitosan-sodium tripolyphosphate (NaTPP) nanoparticle, and evaluate its pharmacokinetic profiles.
Wawaimuli Arozal +4 more
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