Current Drug Targets, 2011 Curcumin (diferuloylmethane), an orange-yellow component of turmeric or curry powder, is a polyphenol natural product isolated from the rhizome of the plant Curcuma longa. For centuries, curcumin has been used in some medicinal preparation or used as a food-coloring agent.
Hongyu, Zhou +2 more
openaire +2 more sources
Antinociceptive and anti-inflammatory actions of curcumin and nano curcumin: a comparative study
Research in Pharmaceutical Sciences, 2023 Background and purpose: Pain and inflammation can be treated by various therapies that for the most part are not effective and can result in adverse effects.
Mojdeh Mohammadi +3 more
doaj +1 more source
Comparison of Inhibitory Effect of Curcumin Nanoparticles and Free Curcumin in Human Telomerase Reverse Transcriptase Gene Expression in Breast Cancer [PDF]
Advanced Pharmaceutical Bulletin, 2013 Purpose: Telomerase is expressed in most cancers, including breast cancer. Curcumin, a polyphenolic compound that obtained from the herb of Curcuma longa, has many anticancer effects. But, its effect is low due to poor water solubility.
Nosratollah Zarghami +2 more
doaj +1 more source
Indonesian Journal of Chemistry, 2023 The usage of antiradical agents is pivotal for suppressing the negative effects of free radicals on human health. Curcumin, a well-known natural antiradical agent, suffers from its low stability and high price, thus, limiting its potential in real ...
Indriana Kartini +4 more
doaj +1 more source
Acetylation: a critical factor in maintaining intestinal inflammation? [PDF]
, 2010 PhDIn inflammatory bowel disease (IBD), both chronic pro-inflammatory pathways and failure of anti-inflammatory (healing) mechanisms sustain disease. The two major anti-inflammatory gut cytokines are transforming growth factor (TGF)-β and interleukin (IL)
Epstein, Jenny
core +3 more sources
Processing Stabilisation of PE with a Natural Antioxidant, Curcumin [PDF]
, 2013 The potential use of natural antioxidants for polyolefin stabilisation came into the centre of attention because of some doubts about the effects of the reaction products of synthetic phenolic antioxidants on human health.
Tátraaljai, Dóra +4 more
core +1 more source
Curcumin Chemosensitizes 5-Fluorouracil Resistant MMR-Deficient Human Colon Cancer Cells in High Density Cultures [PDF]
, 2014 Objective Treatment of colorectal cancer (CRC) remains a clinical challenge, as more than 15% of patients are resistant to 5-Fluorouracil (5-FU)-based chemotherapeutic regimens, and tumor recurrence rates can be as high as 50–60%.
Patricia Kraehe +17 more
core +1 more source
The nontoxic natural compound Curcumin exerts anti-proliferative, anti-migratory, and anti-invasive properties against malignant gliomas [PDF]
, 2010 Background: New drugs are constantly sought after to improve the survival of patients with malignant gliomas. The ideal substance would selectively target tumor cells without eliciting toxic side effects.
Senft, Christian +17 more
core +2 more sources
Visible light is a better co-inducer of apoptosis for curcumin-treated human melanoma cells than UVA [PDF]
, 2013 Curcumin attracts worldwide scientific interest due to its anti-proliferative and apoptosis inducing effects on different tumor cells at concentrations ranging from 10 to 150 µM (3.7–55 µg/ml).
Kerstin Goerg +23 more
core +2 more sources
Antimicrobial Activity of Curcumin and Deuterated Curcumin
Journal of Natural Remedies, 2022 Deuterium (D) and hydrogen (H) are bioisosteres because they are similar in size and shape with alike physiochemical properties and hence expect similar biological activity. The purpose of replacing H with D is to extend the time the active drug species spends in plasma, resulting in increased effectiveness and/or the avoidance of unwanted side effects.
G. V. Anjana, M. K. Kathiravan
openaire +1 more source