Results 1 to 10 of about 5,469 (180)

Phosphorylation of the fission protein Drp1 contributes to the impact of the curcuminoid 1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one on mitochondrial and cellular processes [PDF]

BBA Advances
Curcumin and its curcuminoid derivatives extracted from turmeric have been investigated for their potential therapeutic benefits in cancer treatment. Curcuminoids 1,7-bis(4-hydroxyphenyl)-1,4,6-heptatrien-3-one and bisdemethoxycurcumin can be obtained ...
Navyamol Chakkalaparambil Dileep, Chi-Wei Chiu, Ching-Tse Wu, Chuang-Rung Chang, Chih-Yu Lo   +4 more
doaj   +2 more sources

In vitro cytotoxicity of curcuminoids against head and neck cancer HNO97 cell line

Brazilian Journal of Biology, 2021
Oral squamous cell carcinoma (OSCC) is a malignant tumour of Head and Neck Cancer (HNC). The recent therapeutic approaches used to treat cancer have adverse side effects.
Z. Almalki, M. Algregri, M. Alhosin, M. Alkhaled, S. Damiati, M. A. Zamzami   +5 more
doaj   +1 more source

Novel nanomicelle formulation to enhance bioavailability and stability of curcuminoids [PDF]

Iranian Journal of Basic Medical Sciences, 2019
Objective(s): Curcuminoids, comprising curcumin, demethoxycurcumin (DMC) and bisdemethoxycurcumin (BDMC), are bioactive phytochemicals with numerous pharmacological effects.
Mahdi Hatamipour, Amirhossein Sahebkar, Seyedeh Hoda Alavizadeh, Mahyar Dorri, Mahmoud Reza Jaafari   +4 more
doaj   +1 more source

CURCUMINOIDS: RECOVERY, PROPERTIES AND APPLICATION REPORT 1. RECOVERY OF CURCUMINOIDS AND THEIR PHYSICAL AND CHEMICAL PROPERTIES

Современная наука и инновации, 2023
HPLC method of curcuminoids (curcumin, demetoxycurcumin, bis-demetoxycurcumin) qualitative and quantitative analysis is developed. The protocol of curcuminoids additive preparation recovery from vegetative raw material (Curcuma longa L.) by different ...
M. A. Kapustin, A. S. Chubarova, S. V. Lodygina, A. D. Lodigin, I. A. Evdokimov, А. V. Yantsevich, V. P. Kurchenko   +6 more
doaj   +1 more source

Extractability of Curcuminoids Is Enhanced with Milk and Aqueous-Alcohol Mixtures

Molecules, 2022
In this study, we evaluated the extractability of three curcuminoids (curcumin, demethoxycurcumin, and bisdemethoxycurcumin) from turmeric powder in several solvents using high-performance liquid chromatography (HPLC) with the diode-array detection ...
Raghavendhar R. Kotha, Fakir Shahidullah Tareq, Devanand L. Luthria   +2 more
doaj   +1 more source

Isolation and Structural Characterization of Curcuminoids with Spectral and Chromatographic Techniques

Pakistan Journal of Analytical & Environmental Chemistry, 2023
Curcuminoids are the active ingredients of Curcuma longa L. and are one of the most researched subjects owing to their biological activities. This study focuses on the structural analysis of curcuminoids isolated from turmeric roots using NMR ...
Ayşe ŞAP, Mehmet YAMAN, Emine AKYÜZ TURUMTAY   +2 more
doaj   +1 more source

Curcumin analogues exert potent inhibition on human and rat gonadal 3β-hydroxysteroid dehydrogenases as potential therapeutic agents: structure-activity relationship and in silico docking

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023
Curcuminoids are functional food additives, and the effect on gonadal hormone biosynthesis remains unclear. Gonads contain 3β-hydroxysteroid dehydrogenase isoforms, h3β-HSD2 (humans) and r3β-HSD1 (rats), which catalyse pregnenolone into progesterone. The
Xinyi Qiao, Lei Ye, Jialin Lu, Chengshuang Pan, Qianjin Fei, Yang Zhu, Huitao Li, Han Lin, Ren-shan Ge, Yiyan Wang   +9 more
doaj   +1 more source

Curcuminoid binding to embryonal carcinoma cells: reductive metabolism, induction of apoptosis, senescence, and inhibition of cell proliferation. [PDF]

PLoS ONE, 2012
Curcumin preparations typically contain a mixture of polyphenols, collectively referred to as curcuminoids. In addition to the primary component curcumin, they also contain smaller amounts of the co-extracted derivatives demethoxycurcumin and ...
Wolfgang W Quitschke
doaj   +1 more source

The Demethoxy Derivatives of Curcumin Exhibit Greater Differentiation Suppression in 3T3-L1 Adipocytes Than Curcumin: A Mechanistic Study of Adipogenesis and Molecular Docking

Biomolecules, 2021
Curcumin is a known anti-adipogenic agent for alleviating obesity and related disorders. Comprehensive comparisons of the anti-adipogenic activity of curcumin with other curcuminoids is minimal.
Ahmed Alalaiwe, Jia-You Fang, Hsien-Ju Lee, Chun-Hui Chiu, Ching-Yun Hsu   +4 more
doaj   +1 more source

Impact of cooking on the antioxidant activity of spice turmeric

Food & Nutrition Research, 2019
Curcuminoids, as the main ingredient of turmeric, are popularly used in food additives and condiments, and are widely accepted to be beneficial for human health for their antioxidant activity.
Jian-Long Sun, Hong-Fang Ji, Liang Shen
doaj   +1 more source