Results 81 to 90 of about 1,474,552 (311)

The Cost of Uncertainty in Curing Epidemics

, 2018
Motivated by the study of controlling (curing) epidemics, we consider the spread of an SI process on a known graph, where we have a limited budget to use to transition infected nodes back to the susceptible state (i.e., to cure nodes).
Caramanis, Constantine, Hoffmann, Jessica   +1 more
core   +1 more source

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack, A. Carolina Tufino, Mohd Azrin Jamalruddin, Sreya Dey, Yinghong Pan, Elina Mukherjee, Jessica D. Daley, Julia Meade, Mahmoud Aarabi, Lisa Maurer, James Cooper, Kara A. Bernstein, Kelly M. Bailey   +12 more
wiley   +1 more source

Tumor-specific AAV delivery of interleukin-12 enhances antitumor immunity and safety in ovarian cancer xenograft mouse model

Molecular Therapy: Oncology
Interleukin-12 (IL-12) is a promising pro-inflammatory cytokine for cancer immunotherapy, but its toxicity and short half-life in serum limit its clinical application.
Chuyuan Chen, Yongji Jiang, Chuan Feng, Qingyun Zhou, Xingrong Luo, Lili Cai, Lei Zhao   +6 more
doaj   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell, Kavitha Srivatsa, Paola Angelini, Pei‐Chi Kao, Brady Payne, Arlene Naranjo, Sveva Castelli, Miho Kato, Miki Ohira, Ulriche Pöetschger, Yaël Mossé, Lucas Moreno, Meredith S. Irwin, Ramya Ramanujachar, Wendy B. London   +14 more
wiley   +1 more source

Historical Epistemology as Disability Studies Methodology: From the Models Framework to Foucault’s Archaeology of Cure

Foucault Studies, 2015
In this article, I argue for historical epistemology as a methodology for critical disability studies (DS) by examining Foucault’s archaeology of cure in History of Madness.
Aimi Hamraie
doaj   +1 more source

Chemoviscosity modeling for thermosetting resin systems, part 3 [PDF]

A new analytical model for simulating chemoviscosity resin has been formulated. The model is developed by modifying the well established Williams-Landel-Ferry (WLF) theory in polymer rheology for thermoplastic materials.
Bai, J. M., Hou, T. H.
core   +1 more source

Searching for a Cure for Cancer [PDF]

, 2009
For Professor Anne Kruchten, cancer is more than a disease as she and her students pursue a research agenda to help improve understanding about how the disease ...
Mileham, Mardi
core   +1 more source

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher, Jennifer L. Bernstein, Katia M. Crisler, Julia K. Herriott, Kimberly L. Klages, Robin E. Norris, Mariann L. Strenk, Sarah E. Bills, Meghan E. McGrady   +8 more
wiley   +1 more source

A Systematic Review on the Effectiveness of the Cure Violence Approach

Inquiry: The Journal of Health Care Organization, Provision, and Financing
The Cure Violence approach applies public health epidemic control strategies to reduce violence in highly impacted communities and countries. This paper conducts a systematic review to identify studies analyzing the effectiveness of the Cure Violence ...
Charles Ransford MPP, Monique Williams PhD, Gary Slutkin MD   +2 more
doaj   +1 more source

Transanal Minimally Invasive Surgery for Rectal Cancer

South Asian Journal of Cancer
Transanal minimally invasive surgery (TAMIS) is considered a standard of care in rectal cancers. Its advantage is that it is organ preserving. Its main role is in early-stage cancers limited to the rectum (T1N0M0).
Sheikh Mohammad Taha Mustafa, Deepak Govil, Vijay Arora, V.K. Malik, Shivendra Singh, Avinash Saklani, Rajesh Bhojwani, Shyam Aggarwal, Purvish M. Parikh, C. Selvasekar, Saumitra Rawat   +10 more
doaj   +1 more source