Results 111 to 120 of about 286,510 (260)

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Study of the Properties of a Plain Cathode Grimm-Type DC Glow Discharge Source Operated in a Current-Controlled Pulse Regime [PDF]

open access: yes, 2012
Glow discharge sources have been used for analytical purpose for several years. Recently the pulsed operation mode has gained an increasing importance.
Bánhidi, Olivér
core  

Astrocyte heterogeneity in brain metastases

open access: yesMolecular Oncology, EarlyView.
Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver   +2 more
wiley   +1 more source

Feasibility of high frequency alternating current power distribution for the automobile auxiliary electrical system [PDF]

open access: yes, 2011
This study investigates the feasibility and potential benefits of high frequency alternating current (HFAC) for vehicle auxiliary electrical systems. A 100Vrms, 50kHz sinusoidal AC bus is compared with 14V DC and 42V DC electrical systems in terms of ...
Antaloae, C. C.
core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Modulação vetorial aplicada a retificadores trifásicos PWM unidirecionais [PDF]

open access: yes, 2006
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Elétrica.Este trabalho apresenta a aplicação da modulação vetorial a retificadores trifásicos PWM unidirecionais de dois níveis.
Batista, Flabio Alberto Bardemaker
core  

Thermoelectric device for transpalpebral hypothermia of the anterior segment of the human eyeball

open access: yesВестник Дагестанского государственного технического университета: Технические науки
Objective. The purpose of the study is to develop the design of a thermoelectric device for transpalpebral hypothermia of the anterior segment of the human eyeball.Method.
O. V. Evdulov   +4 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Conexão série-série de módulos CC-CC isolados [PDF]

open access: yes, 2015
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia Elétrica, Florianópolis, 2015Esta tese apresenta a associação de conversores CC-CC de duas portas conectados em série-série tanto na ...
Bottion, Antonio José Bento
core  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

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