Results 51 to 60 of about 2,518,854 (336)
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Reinspection of curriculum areas 1996-97: report from the Inspectorate [PDF]
, 1997 FEFC INSPECTION REPORT 109/97 REINSPECTION OF CURRICULUM AREAS, OCTOBER 1996 TO MAY 1997 The Council has agreed that colleges with curriculum areas judged by the inspectorate to have more weaknesses than strengths (grades 4 or 5) may have their ...
core
Auditing the Numeracy Demands of the Middle Years Curriculum [PDF]
, 2012 The National Numeracy Review Report recognized that numeracy development requires an across the curriculum commitment. To explore the nature of this commitment we conducted a numeracy audit of the South Australian Middle Years curriculum, using a ...
Dole, Shelley +2 more
core +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
CURRICULUM DOCUMENT, CURRICULUM PERFORMANCE
, 2020 Neste texto busca-se mostrar o enlace entre currículos e performance. Tal intento se opõe ànoção de currículo como documento. Circunscreve-se as noções de ficção e de corpo no campo daperformance, bem como nas produções que entrelaçam os Estudos da Performance com o campo daEducação. Apresenta-se uma revisão das principais referências sobre Performance
ATHAYDE PAZ, LUCIANA, ICLE, GILBERTO
openaire +1 more source
Freshwater Macroinvertebrates [PDF]
, 2003 The purpose of this resource is to sample, identify, and count macroinvertebrates at a Hydrology Site. Students collect, sort, identify, and count macroinvertebrates from habitats at their site.
The GLOBE Program, UCAR (University Corporation for Atmospheric Research)
core
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
View of curriculum experts and postgraduate students regarding the quality of students' participation in curriculum development [PDF]
رویکردهای نوین آموزشی, 2013 The aim of this study was to investigate the postgraduate students' views regarding their current and desired participation in curriculum development and compare their views with the curriculum experts' opinions.
F. Sharifian +3 more
doaj