Results 41 to 50 of about 1,014,024 (368)

Curriculum, Empiricisms, and Post-Truth Politics

open access: yes, 2019
The purpose of this paper is to approach the phenomenon of post-Truth politics as an important site of inquiry for the field of curriculum theory. The authors define curriculum as the empirical frameworks that shape our acts of knowing, being, and ...
Franklin-Phipps, Asilia   +1 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The Healthy School Pattern Development : A Qualitative Study [PDF]

open access: yesPizhūhish/hā-yi rahbarī va mudīriyyat-i āmūzishī, 2018
Introduction: Turning a school into a healthy place is one of the challenges for anyone involved in any educational system. The aim of this study was to develop a healthy school model and provide a comprehensive model using experimental and conceptual ...
Ali Javidan   +3 more
doaj   +1 more source

Knitting Curriculum: Storied Threads of Pre-Service Art Teaching

open access: yes, 2012
In this paper, we explore a knitted curriculum. Connecting the traditional craft of knitting with meaning-making, art, and activism, we attempt to understand live(d) curriculum through two pre-service teachers' unique experiences.
LaJevic, Lisa M, Powell, Kimberly
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Disability Plots: Curriculum, Allegory, & History

open access: yes, 2019
This article discusses theoretical approaches from disability studies and curriculum studies to help educators see how we position the experiences of, and discourses about, people with disabilities in the various narratives we recreate about “America ...
Helmsing, Mark
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

‘Imagine and Make’ pedagogy: impacts of combining Entrepreneurial Thinking, Design Thinking and 3D Printing technology on the learning experience in general education

open access: yesCogent Education
Entrepreneurial Thinking, Design Thinking, and 3D Printing are traditionally applied separately in specialized curricula but are increasingly integrated to enrich learning and foster essential skills.
Imen Said   +4 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Differentiating instruction in primary and middle schools: Does variation in students’ learning attributes matter?

open access: yesCogent Education, 2022
This study sought to determine the significant relationship between student attributes (background knowledge, readiness, interests, and learning profiles) and the teachers’ use of DI elements (content, process, product, and learning environment ...
Tadesse Melesse, Sinatayehu Belay
doaj   +1 more source

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