Results 51 to 60 of about 1,192,007 (292)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
度量化的身體：學校體適能檢測的權力技術 The Quantified Body: The Technique of Power of Physical Fitness Tests at School
臺灣教育社會學研究, 2014 本論文藉由跨領域的形式提供另一種體適能的研究觀點。從分析學校體適能的檢測機制，探討其對學生身體規訓與抵抗的可能。基於這樣的理念與架構，研究者先以自己任教健體領域的六年級學生為對象，透過兒童哲學形式的討論，並考量性別均衡與體適能常模的常態分布後，選出10位六年級學生作為主要訪談對象。此外，為了瞭解體適能檢測的權力關係如何運作，研究者除了參加體適能檢測員的培訓外，也選擇兩所熟識的國小進行觀察。本研究發現如下：一、體適能檢測透過柔軟度的訓練、身體被看見的安排、體適能護照的登錄、常模的規範化裁決 ...
陳鴻文Hung-Wen Chen
doaj +1 more source
A model of active student participation in curriculum design: exploring desirability and possibility [PDF]
, 2011 This paper explores the desirability and possibility of active student participation (ASP) in curriculum design. Rationales for pursuing ASP in curriculum design are outlined.
Bovill, C., Bulley, C.J.
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Shizi Peiyu Yu Jiaoshi Zhuanye Fazhan Qikan, 2010 本研究透過系統化教學設計之方式，融合教科書之主要語法結構，發展出適合國中七年級學生的英語寫作教學課程。 本研究得到之研究結論如下： 一、Dick 和 Carey 的系統化教學設計理念，能協助教學者設立明確的教學目標。 二、研究對象填寫之「英語造句書寫興趣量表」前後測，以成對樣本t 檢定分析， 顯示以系統化教學設計英語造句寫作課程，能提升學習者的英語造句書寫興趣。 三、量表中四個分量表－「個人寫作知覺」、「寫作技巧」、「寫作喜好」和「英語學 習態度」之前後測，進行成對樣本t 檢定 ...
林婕婷 Lin, Chieh-Ting +2 more
doaj
Curriculum integration as treaty praxis. [PDF]
, 2002 The article discusses the significance of curriculum integration on the promotion of principles of the Treaty of Waitangi, an agreement signed in 1840 by the Maori and the Crown people in New Zealand.
Fraser, Deborah, Parah, Hokimate
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Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
South African Journal of Education, 2017 The concept of student teaching practice is globally rooted in training pre-service teachers to work within diverse schools and learner populations, in dissimilar contexts.
Thabisile Nkambule +1 more
doaj +1 more source
Contours of Inclusion: Inclusive Arts Teaching and Learning [PDF]
, 2010 The purpose of this publication is to share models and case examples of the process of inclusive arts curriculum design and evaluation. The first section explains the conceptual and curriculum frameworks that were used in the analysis and generation of ...
Bill Henderson +6 more
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source