Results 71 to 80 of about 993,604 (284)

Evaluation of the implementation of curriculum materials for civics in the Netherlands [PDF]

, 1995
Discusses a study evaluating the implementation of curriculum materials for civics in the Netherlands. Pedagogical principles aimed at increasing students' social commitment; Central research question; Exploration of broad context for implementation ...
Akker, Jan van den, Kuiper, Wilmad
core   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

Molecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

RECONCEPTUALIZAREA EVALUĂRII CURRICULUMULUI UNIVERSITAR

Studia Universitatis Moldaviae: Stiinte ale Educatiei, 2018
În articol este abordată problema privind evaluarea curriculumului universitar din perspectiva postmodernității. Accentul se pune pe definirea curriculumului universitar în calitate de obiect al evaluării, pe analiza diferitelor modele de evaluare a ...
Vladimir Guțu
doaj  

Interdisciplinary Shadowing and Case Discussion Improve Medical Students’ Self-Efficacy and Attitude Toward Discharge Planning

Journal of Multidisciplinary Healthcare, 2023
Yi-Cheng Li,1,2 Yia-Ling Chang,3 Fang-Yih Liaw,2,4 Chih-Chia Wang,2,4 Yaw-Wen Chang2,4 1Department of Family Medicine, Hualien Armed Forces General Hospital, Hualien, Taiwan, Republic of China; 2School of Medicine, National Defense Medical Center, Taipei,
Li YC, Chang YL, Liaw FY, Wang CC, Chang YW   +4 more
doaj  

Principles in Patterns (PiP) : User Acceptance Testing of Course and Class Approval Online Pilot (C-CAP) [PDF]

, 2012
The PiP Evaluation Plan documents four distinct evaluative strands, the first of which entails an evaluation of the PiP system pilot (WP7:37 – Systems & tool evaluation).
Macgregor, George
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Developing theoretical rigour in inter professional education [PDF]

, 2014
In this chapter, the author explores the meaning of theory and the role it plays in the development of interprofessional education. The chapter explores specifically the utility of the theory of social capital in the field and uses this as a case theory ...
Hean, Sarah
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

The measurement of stereotypes in the evaluation of Interprofessional Education [PDF]

, 2009
This chapter is directed at evaluators using student stereotypes of health and social care (HSC) professionals to understand the processes and outcomes of Interprofessional Education (IPE) programmes.
Hean, Sarah
core   +1 more source