Results 81 to 90 of about 6,160,901 (255)
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Review and Perspectives on school-based Curriculum Evaluation in Taiwan
, 2013 現行九年一貫課程鋼要賦予國中小學發展課程的權責，並要求學校必須針對自身的課程進行評鑑。因此，繼「學校本位課程發展」之後，「學校本位課程評鑑」成為當前學術界與實務界關心的重要議題。本文旨在探討臺灣學校本位課程評鑑的研究現況，首先論述學校本位課程評鑑的概念與途徑，其次分析近十年(1998-2008)學術研究的數量、主題與途徑，最後對未來的研究方向提出建議。The current 1-9 Curriculum Framework empowers elementary and middle schools ...
游家政
core
Health Behavior ResearchPhysical activity (PA) and social-emotional learning (SEL) are critical for healthy development, yet few programs have evaluated integrated promotion efforts within out-of-school summer contexts.
Tyler Prochnow +5 more
doaj +1 more source
Extending Pharmacist Roles in Primary Healthcare to Meet the Needs of Universal Health Coverage in Zimbabwe: A Pharmacist Perspective and Curriculum Evaluation. [PDF]
Pharmacy (Basel), 2022 Chiutsi D, Suleman F, Perumal-Pillay VA.
europepmc +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
Annual corporate evaluation report 2000 [PDF]
, 2000 French version available in IDRC Digital Library: Rapport annuel sur l'évaluation 2000The Annual Corporate Evaluation (ACE) Report is an element of the Centre's performance monitoring and reporting system.
IDRC. Evaluation Unit
core
Knitting Curriculum: Storied Threads of Pre-Service Art Teaching [PDF]
, 2012 In this paper, we explore a knitted curriculum. Connecting the traditional craft of knitting with meaning-making, art, and activism, we attempt to understand live(d) curriculum through two pre-service teachers' unique experiences.
LaJevic, Lisa M, Powell, Kimberly
core +1 more source
Shaping the Future of Interior Design in Saudi Arabia: A Comprehensive Program Evaluation [PDF]
JES: Journal of Engineering SciencesOver time, the job market has become more complex and demands a wider range of skills from graduates. Research shows that stakeholders have varying expectations for entry-level interior designers in terms of skills, competencies, and attributes.
Samaher Fallatah
doaj +1 more source
The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity
FEBS Open Bio, EarlyView.Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav +4 more
wiley +1 more source