Results 91 to 100 of about 267,369 (299)

Evaluation and zoning of soil erosion potential using geomorphometric indexes and Fuzzy approach in Khiavchai watershed, Meshginshahr [PDF]

open access: yesمطالعات جغرافیایی مناطق خشک
Aim: Erosion is a critical geomorphological process with significant environmental implications, including land degradation, fertility loss, and negative effects on aquatic ecosystems.
Faraiba Esfandyari Darabad   +3 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

An approximate solution for modes of curved optical fiber

open access: yesФизика волновых процессов и радиотехнические системы, 2019
The paper presents an approximate analytical solution in closed form for the mode of a weakly guiding circular optical fiber with an arbitrary profile of the refractive index.
V.A. Burdin   +2 more
doaj   +1 more source

Novel Topological Phase with a Zero Berry Curvature [PDF]

open access: green, 2017
Feng Liu, Katsunori Wakabayashi
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Membrane curvature underlies actin reorganization in response to nanoscale surface topography [PDF]

open access: bronze, 2019
Hsin-Ya Lou   +10 more
openalex   +1 more source

On the Sectional Curvature of Holomorphic Curvature Operators [PDF]

open access: yesProceedings of the American Mathematical Society, 1981
Guerrero, Ignacio, Zoltek, Stanley M.
openaire   +2 more sources

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

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