Results 81 to 90 of about 103,223 (251)

Correction. Connect The Dots: How Many Random Points Can A Regular Curve Pass Through?

open access: yes, 2006
Correction for Adv. in Appl. Probab. 37, no.
Arias-Castro, E.   +3 more
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Scheme and Analysis of a Kind of Suspended Monorail’s Bogie Structure

open access: yes机车电传动, 2015
With analyzing characteristics of German produced H-BAHN suspended monorail, and based on the domestic and foreign current standards specifications, and the related patents and literature as well as other related information, a suspended monorail’s bogie
JIANG Yongzhi, WANG Yueming, XIE Qian
doaj  

Log-Cubic Method for Generation of Soil Particle Size Distribution Curve

open access: yesThe Scientific World Journal, 2013
Particle size distribution (PSD) is a fundamental physical property of soils. Traditionally, the PSD curve was generated by hand from limited data of particle size analysis, which is subjective and may lead to significant uncertainty in the freehand PSD ...
Songhao Shang
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

High-mountain DMUs Exporting to Sri Lanka Railway

open access: yes机车电传动, 2014
Technical parameter, characteristics and overall layout of DMUs for Sri Lanka railway high-mountain line were introduced.Field tests were put forward including traction accelerated velocity, highest operation velocity, braking distance, performance of ...
YANG Xingqing   +3 more
doaj  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Influence of Electromagnetic Force on Curve PassingDynamic Performance of LIM Metro Vehicle

open access: yes机车电传动, 2016
Three-dimensional electromagnetic forces (longitudinal, vertical and lateral electromagnetic force) produced between theprimary and secondary of linear induction motor (LIM), may influence the dynamic performance of LIM vehicle.
LIU Gaokun
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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