Results 91 to 100 of about 12,792 (246)

Sex‐Based Differences in Noncommunicable Diseases in Older Adults: Raising the Profile of Older Females

open access: yes
Journal of the American Geriatrics Society, EarlyView.
Aathmika Nandan   +2 more
wiley   +1 more source

Mitigating subtherapeutic cabozantinib exposure after prior mitotane therapy in adrenocortical carcinoma: Pharmacological boosting with cobicistat

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 606-611, February 2026.
Mitotane is an adrenolytic drug with cytotoxic effects, registered for the treatment of advanced adrenocortical carcinoma (ACC), a rare but aggressive tumour type with a poor prognosis despite treatment. Recently, the oral multi‐kinase inhibitor cabozantinib has shown promising results as a potential second‐line treatment option.
Annemieke M. Peters van Ton   +4 more
wiley   +1 more source

Growth Hormone–Releasing Peptides: Investigation of Their Secondary Structure, Thermal Stability, and Model Membrane Interactions

open access: yesChirality, Volume 38, Issue 2, February 2026.
Eight growth hormone–releasing peptides were analyzed by electronic circular dichroism spectroscopy, including evaluation of their thermal stability and interactions with model membranes. In the selected case, occurring interactions were successfully described by the density functional theory calculations, revealing how model membranes affected ...
František Králík   +4 more
wiley   +1 more source

Immune Rebound: Multiple Sclerosis after Treatment of Cushing’s disease [PDF]

open access: yesIranian Journal of Immunology, 2016
High cortisol level in endogenous Cushing’s syndrome suppresses the immune system and after treatment there may be an over activity of immune reaction leading to autoimmune diseases mostly thyroid and rheumatologic disorders.
Mahmood Soveid, Peyman Petramfar
doaj  

Transient 7‐hour coma following a sacrococcygeal epidural with ropivacaine in a cat

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 2‐year‐old cat was anaesthetised for pelvic fracture repair. Premedication included methadone 0.2 mg/kg and medetomidine 5 µg/kg intravenously (IV). Anaesthesia was induced with ketamine 2 mg/kg and propofol 1 mg/kg IV and maintained with isoflurane.
Morgane Gavet   +4 more
wiley   +1 more source

Prolonged survival in a young Dobermann with adrenal neuroblastoma

open access: yesVeterinary Record Case Reports, Volume 14, Issue 1, February 2026.
Abstract A 1‐year‐old Dobermann presented with recurrent episodes of acute diarrhoea and weight loss starting at 5 months of age. An adrenal mass was identified via ultrasound and computed tomography, leading to adrenalectomy. A diagnosis of adrenal neuroblastoma was obtained through histopathology and immunohistochemistry.
Nataliia Ignatenko   +8 more
wiley   +1 more source

A Retrospective Study on the Impact of Primary Aldosteronism in Pregnancy (H.A.P.P.I. Study Group)

open access: yesClinical Endocrinology, Volume 104, Issue 2, Page 113-122, February 2026.
ABSTRACT Objective Primary aldosteronism (PA) is a common cause of hypertension in young women. However, there is a paucity of data regarding its impact during pregnancy. The primary objective of this study was to describe the occurrence of hypertensive disorders of pregnancy (HDP) in PA.
Diana Oprea   +7 more
wiley   +1 more source

Impact of Symptoms of Neuromyelitis Optica Spectrum Disorder and Patient‐Determined Oral Glucocorticoid–Related Adverse Events on Patients' Daily Living and Emotions: A Qualitative Analysis From Japan

open access: yesClinical and Experimental Neuroimmunology, Volume 17, Issue 1, February 2026.
ABSTRACT Background and Objectives Neuromyelitis optica spectrum disorder (NMOSD) is a chronic disorder with a relapsing–remitting disease course that impacts patients' quality of life. Oral glucocorticoids (OGCs) have been the standard of care for NMOSD in Japan; however, their chronic use is associated with adverse events (AEs).
Yuko Shimizu   +7 more
wiley   +1 more source

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