Results 21 to 30 of about 12,792 (246)

Fluconazole for Hypercortisolism in Cushing’s Disease: A Case Report and Literature Review

Frontiers in Endocrinology, 2020
BackgroundCushing’s disease is associated with an increased risk of pulmonary fungal infection, which could be a relative contraindication for pituitary adenoma excision surgery.CaseWe report a case of a patient with Cushing’s disease and pulmonary ...
Yiming Zhao, Weiwei Liang, Feng Cai, Qun Wu, Yongjian Wang   +4 more
doaj   +1 more source

An extremely rare case of calcinosis cutis in human Cushing’s disease

Endocrinology, Diabetes & Metabolism Case Reports, 2022
Cushing’s disease or pituitary adrenocorticotropic hormone (ACTH)-dependent Cushing’s syndrome is considered a rare condition. It is caused by hypersecretion of the ACTH by a pituitary adenoma that ultimately induces endogenous hypercortisolism by ...
Najoua Rbiai, Ikram Mahroug, Nada Zizi, Hanane Latrech   +3 more
doaj   +1 more source

An Unusual Case of Cushing’s Syndrome: Coexistence of Functional Pituitary and Adrenal Adenoma

Haseki Tıp Bülteni, 2017
A case of adrenocorticotropic hormone (ACTH)-independent Cushing’s syndrome, which develops in the course of ACTH-dependent Cushing’s disease, is presented in this report.
Muzaffer İlhan, Özcan Karaman, İrem Yasin Çetin, Nur Büyükpınarbaşılı, Jamshid Hamdard, Ertuğrul Taşan   +5 more
doaj   +1 more source

Invasive fungal infections in endogenous Cushing’s syndrome

Infectious Disease Reports, 2010
Cushing’s syndrome is a condition characterized by elevated cortisol levels that can result from either augmented endogenous production or exogenous administration of corticosteroids.
Rafael Selbach Scheffel, José Miguel Dora, Letícia Schwerz Weinert, Valério Aquino, Ana Luiza Maia, Luis Henrique Canani, Luciano Z. Goldani   +6 more
doaj   +1 more source

Osilodrostat‐induced adrenal insufficiency in a patient with Cushing's disease

Clinical Case Reports, 2022
Cushing's disease is a rare condition caused by a benign pituitary tumor underlying adrenocorticotropic hormone excess. Medical treatment is implemented when surgical resection is not curative.
Catherine Ekladios, Jessica Khoury, Shahzad Mehr, Krystel Feghali   +3 more
doaj   +1 more source

High recovery rate of adrenal function after successful surgical treatment of Cushing’s syndrome

Endocrine Connections
Context: Successful first-line treatment of Cushing’s syndrome by resection of the underlying tumor is usually followed by adrenal insufficiency. Purpose: The aims of this study were to determine the recovery rate and time to recovery of adrenal function
Annenienke C van de Ven, Pepijn van Houten, Lisan Grevers, Henri J L M Timmers, Erik van Lindert, Johan F Langenhuijsen, Romana T Netea-Maier   +6 more
doaj   +1 more source

A challenging case of Cushing’s disease complicated with multiple thrombotic phenomena following trans-sphenoidal surgery; a case report

BMC Endocrine Disorders, 2021
Background Cushing’s syndrome occurs due to overproduction of cortisol from adrenal glands. Endogenous hypercortisolemia can occur secondary to adrenocorticotropic hormone (ACTH) dependent as well as independent causes.
Piyumi Sachindra Alwis Wijewickrama, Vithiya Ratnasamy, Noel P. Somasundaram, Manilka Sumanatilleke, Sathyajith Buddhika Ambawatte   +4 more
doaj   +1 more source

Cushing’s disease and bipolar disorder: study of medicopsychiatric intricacies from a clinical vignette

European Psychiatry, 2023
Introduction Cushing’s syndrome is a relatively rare condition that results from chronic hypercortisolism. This syndrome is characterized by the presence of various psychiatric manifestations that can accompany it at all its stages of evolution.
F. Z. Chamsi, H. Abrebak, T. amine, A. El ammouri   +3 more
doaj   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source