Results 41 to 50 of about 12,049 (277)

Delayed diagnosis of Cushing's disease in a pediatric patient due to apparent remission from spontaneous apoplexy

Journal of Clinical and Translational Endocrinology Case Reports, 2016
We report here a pediatric patient whose Cushing's Disease was diagnosed late because of her cyclical presentation, presumably due to subclinical pituitary apoplexy.
Sara H. Rahman, Prashant Chittibonia, Martha Quezado, Nicholas Patronas, Constantine A. Stratakis, Maya B. Lodish   +5 more
doaj  

Adverse Cardiovascular Risk Profile and Increased Diurnal Salivary Cortisol in Girls With Turner Syndrome: An Exploratory Study

American Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Patients with Turner Syndrome (TS) and those exposed to high concentrations of glucocorticoids have a number of characteristics in common, including an increased risk of cardiovascular disease. Pediatric TS patients underwent studies of salivary cortisol (SC) and cortisone (SCn), body composition, continuous glucose monitoring, vascular ...
Lily Jones, Julie Park, Silothabo Dliso, Daniel B. Hawcutt, Alena Shantsila, Gregory Y. H. Lip, Joanne Blair   +6 more
wiley   +1 more source

An integrated clinical score to predict remission in cushing's disease

Indian Journal of Endocrinology and Metabolism, 2023
Objective: To derive a clinical score from parameters that favor remission of Cushing's disease (CD) after pituitary surgery. Methods: This is an analysis of 11 clinical, hormonal, and post-operative parameters that each favored remission in a cohort of ...
Nidhi Gupta, Aditya Dutta, Mintu Mani Baruah, Anil Bhansali, Chirag Kamal Ahuja, Sivashanmugam Dhandapani, Sanjay Kumar Bhadada, Uma Nahar Saikia, Rama Walia   +8 more
doaj   +1 more source

Efficacy, Safety, Pharmacokinetics, and Immunogenicity of ABBV‐154 in Adults With Glucocorticoid‐Dependent Polymyalgia Rheumatica: A Phase 2, Randomized, Double‐Blind, Placebo‐Controlled Trial

Arthritis &Rheumatology, EarlyView.
Objective An unmet need exists for glucocorticoid‐sparing treatments for patients with polymyalgia rheumatica (PMR). The antibody‐drug conjugate ABBV‐154 comprises adalimumab conjugated to a glucocorticoid receptor modulator. We evaluated ABBV‐154 versus placebo in patients with glucocorticoid‐dependent PMR.
Robert F. Spiera, Valerie Devauchelle‐Pensec, Claire E. Owen, Federico Díaz‐González, Tsutomu Takeuchi, Edit Drescher, Jaclyn Anderson, Dilek Arikan, Ronilda D'Cunha, Julie Parmentier, Denise T. Kruzikas, Weihan Zhao, Yang Yang, Karen Stellpflug, Frank Buttgereit   +14 more
wiley   +1 more source

Cushing's Disease

, 2007
openAccessArticle: False ; cover date: 2015-01-01 ; pii: B978-0-12-801238-3.04947-3 ; Harvest Date: 2016-01-06 13:08:10 ; issueName: ; Page Range: - ; href scidir: http://www.sciencedirect.com/science/article/pii/B9780128012383049473 ; pubType:
G., Galasko, Galasko, G.
openaire   +2 more sources

Efficacy and Safety of ABBV‐154 for the Treatment of Active Rheumatoid Arthritis: A Phase 2b, Randomized, Placebo‐Controlled Trial

Arthritis &Rheumatology, Accepted Article.
Objective Despite availability of biologics and targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) to treat rheumatoid arthritis (RA), many patients do not experience optimized disease control. Glucocorticoids are effective but have safety risks.
Frank Buttgereit, Atul Singhal, Alan Kivitz, Edit Drescher, Yoshinori Taniguchi, Rosalía Martínez Pérez, Jaclyn Anderson, Ronilda D'Cunha, Weihan Zhao, Nicholas DeVogel, Julie Parmentier, Romy Christmann, Dilek Arikan, Howard Amital   +13 more
wiley   +1 more source

Widespread reductions of white matter integrity in patients with long-term remission of Cushing's disease

NeuroImage: Clinical, 2014
Background: Hypercortisolism leads to various physical, psychological and cognitive symptoms, which may partly persist after the treatment of Cushing's disease.
Steven J.A. van der Werff, Cornelie D. Andela, J. Nienke Pannekoek, Onno C. Meijer, Mark A. van Buchem, Serge A.R.B. Rombouts, Roos C. van der Mast, Nienke R. Biermasz, Alberto M. Pereira, Nic J.A. van der Wee   +9 more
doaj   +1 more source

Essential work, invisible workers: The role of digital curation in COVID‐19 Open Science

Journal of the Association for Information Science and Technology, Volume 76, Issue 4, Page 703-717, April 2025.
Abstract In this paper, we examine the role digital curation practices and practitioners played in facilitating open science (OS) initiatives amid the COVID‐19 pandemic. In Summer 2023, we conducted a content analysis of available information regarding 50 OS initiatives that emerged—or substantially shifted their focus—between 2020 and 2022 to address ...
Irene V. Pasquetto, Amina A. Abdu, Natascha Chtena   +2 more
wiley   +1 more source

Pediatric Cushing's disease: Case reports and retrospective review

Biomedical Papers
Background. We report four pediatric subjects with Cushing's disease (CD) diagnosed in the Czech Republic. We focus on initial symptoms of Cushing's syndrome (CS) which can lead to early diagnosis, on typical symptoms of CS in children, their age and sex
Renata Pomahacova, Petra Paterova, Eva Nykodymova, Josef Sykora, Michal Krsek   +4 more
doaj   +1 more source

Pasireotide‐induced hyperglycemia in a patient with Cushing's disease: Potential use of sodium‐glucose cotransporter 2 inhibitor and glucagon‐like peptide‐1 receptor agonist for treatment

Clinical Case Reports, 2020
Pasireotide improves hypercortisolemia and induces hyperglycemia via somatostatin receptor type‐5 stimulation. GLP‐1RA and SGLT2 inhibitor potentially help regulate hyperglycemia in patients with Cushing's disease, especially after pasireotide ...
Masato Shikata, Kenji Ashida, Yuka Goto, Ayako Nagayama, Shimpei Iwata, Mamiko Yano, Nao Hasuzawa, Kento Hara, Kazutoshi Mawatari, Kiyohiko Sakata, Munehisa Tsuruta, Nobuhiko Wada, Masatoshi Nomura   +12 more
doaj   +1 more source