Results 31 to 40 of about 6,492 (176)

Osteoporotic vertebral compression fractures caused by Cushing’s syndrome in young women: case report and literature review

BMC Musculoskeletal Disorders, 2023
Background Cushing’s syndrome is known as an important cause of secondary osteoporosis, characterized by reduction of bone mineral density and potential occurrence of fragility fractures before diagnosis in young population. Therefore, for young patients
Jie Cheng, Songli Ju, Zihan Zhang
doaj   +1 more source

Cushing’s syndrome: An overview

Journal of Nepal Medical Association, 2006
Cushing’s syndrome is the collection of symptoms and signs caused by chronic elevation of circulating free cortisol. Since the first description of the syndrome, results from long-term exposure to glucocorticoids has not been improved upon, but our ...
R Cincu, Amit Agrawal
doaj   +1 more source

High recovery rate of adrenal function after successful surgical treatment of Cushing’s syndrome

Endocrine Connections
Context: Successful first-line treatment of Cushing’s syndrome by resection of the underlying tumor is usually followed by adrenal insufficiency. Purpose: The aims of this study were to determine the recovery rate and time to recovery of adrenal function
Annenienke C van de Ven, Pepijn van Houten, Lisan Grevers, Henri J L M Timmers, Erik van Lindert, Johan F Langenhuijsen, Romana T Netea-Maier   +6 more
doaj   +1 more source

Endothelial progenitor cells in a patient with Cushing's syndrome before and after adrenal surgery

Journal of Clinical and Translational Endocrinology Case Reports, 2018
Endothelial progenitor cells (EPCs) exert a pivotal role in vascular repairing and vascular function. Low EPCs levels have been detected in patients with endocrine disease at increased cardiovascular risk such as diabetes, hypothyroidism, and ...
Roberto Negro
doaj   +1 more source

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

A rare case of an ACTH/CRH co-secreting midgut neuroendocrine tumor mimicking Cushing’s disease

Endocrinology, Diabetes & Metabolism Case Reports, 2017
Ectopic ACTH/CRH co-secreting tumors are a very rare cause of Cushing’s syndrome and only a few cases have been reported in the literature. Differentiating between Cushing’s disease and ectopic Cushing’s syndrome may be particularly difficult if ...
Regina Streuli, Ina Krull, Michael Brändle, Walter Kolb, Günter Stalla, Marily Theodoropoulou, Annette Enzler-Tschudy, Stefan Bilz   +7 more
doaj   +1 more source

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Subclinical Cushing’s syndrome

Best Practice & Research Clinical Endocrinology & Metabolism, 2012
The routine use of abdominal procedure has significantly increased the incidental finding of adrenal masses. The prevalence of these tumors, commonly defined as adrenal incidentalomas, ranges between 2-3% in autopsy and 4% in radiological series, reaching 5-8% in oncological studies and increasing with patients age. Although clinically silent, in 5-20%
De Leo M, Cozzolino A, COLAO, ANNAMARIA, PIVONELLO, ROSARIO   +3 more
openaire   +8 more sources

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

Exogenous Cushing's syndrome secondary to intermittent high dose oral prednisone for presumed asthma exacerbations in the setting of multiple emergency department visits

Journal of Clinical and Translational Endocrinology Case Reports, 2017
Glucocorticoid therapies are extensively used in a wide range of medical conditions including respiratory, allergic, inflammatory and autoimmune diseases.
Sanjay Manubolu, MD, MPH, Oguchi Nwosu, MD, FAAFP   +1 more
doaj   +1 more source