Results 61 to 70 of about 2,296,742 (335)

Hyperandrogenemia Induces Trophoblast Ferroptosis and Early Pregnancy Loss in Patients With PCOS via CMA‐Dependent FTH1 Degradation

Advanced Science, EarlyView.
In PCOS patients with hyperandrogenemia, decreased ferritin heavy chain 1 (FTH1) causes Fe2⁺ overload and ferroptosis in trophoblasts. Androgens induce FTH1 protein degradation via AR‐LAMP2A‐mediated chaperone‐mediated autophagy pathway, leading to placental development disruption and early pregnancy loss. Metformin mitigates androgen‐induced placental
Hanjing Zhou, Weijie Yang, Na Liu, Qing Liu, Jiamin Jin, Chenqiong Zhao, Xiaoying Jin, Miao Gui, Haiyan Zhu, Songying Zhang, Yinli Zhang   +10 more
wiley   +1 more source

Subclinical Cushing’s syndrome

Best Practice & Research Clinical Endocrinology & Metabolism, 2012
The routine use of abdominal procedure has significantly increased the incidental finding of adrenal masses. The prevalence of these tumors, commonly defined as adrenal incidentalomas, ranges between 2-3% in autopsy and 4% in radiological series, reaching 5-8% in oncological studies and increasing with patients age. Although clinically silent, in 5-20%
De Leo M, Cozzolino A, COLAO, ANNAMARIA, PIVONELLO, ROSARIO   +3 more
openaire   +8 more sources

Harvey Cushing and Philip Hench: pituitary basophilism meets cortisone excess [PDF]

, 2007
Universidade Federal de São Paulo (UNIFESP) Departamento de Medicina Disciplina de EndocrinologiaUniversidade Federal de Pernambuco Hospital das Clínicas Divisão de EndocrinologiaUniversity of Sheffield School of Medicine and Biomedical Science ...
Kater, Claudio Elias, Newell-Price, John, Vilar, Lucio   +2 more
core   +1 more source

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

Complications of Cushing's syndrome: state of the art [PDF]

, 2016
Cushing's syndrome is a serious endocrine disease caused by chronic, autonomous, and excessive secretion of cortisol. The syndrome is associated with increased mortality and impaired quality of life because of the occurrence of comorbidities.
Biller, Beverly M. K, Colao, Annamaria, De Martino, Maria Cristina, Isidori, Andrea, Newell Price, John, Pivonello, Rosario   +5 more
core   +1 more source

Atypical Visually Guided Precision Grip Control in Middle‐Aged and Older Autistic Adults

Autism Research, EarlyView.
ABSTRACT Sensorimotor impairments are well documented in autism spectrum disorder (ASD). However, little is known about how these difficulties present in middle‐aged and older autistic adults or how they relate to demographic factors and autistic traits.
Zheng Wang, Hang Qu, Danielle Christensen, Hanna M. Gemmell, Ellen M. Parks, Kyla E. Wetherington, Ann‐Marie Orlando, Regilda A. Romero, Bikram Karmakar, David E. Vaillancourt   +9 more
wiley   +1 more source

Prolonged adrenal insufficiency after unilateral adrenalectomy for Cushing′s Syndrome

Indian Journal of Endocrinology and Metabolism, 2015
The contralateral healthy adrenal in patients undergoing unilateral adrenalectomy for Cushing′s is known to be suppressed temporarily and forms the basis of peri and postoperative steroids.
Bindu Kulshreshtha, Arpita Arora, Anshita Aggarwal, Minakshi Bhardwaj   +3 more
doaj   +1 more source

Development of serum dexamethasone radioimmunoassay to corroborate Cushing's syndrome diagnosis [PDF]

, 2011
INTRODUCTION: The 1 mg dexamethasone suppression test (DxST) is widely used to screen Cushing's syndrome (CS) due to its high diagnostic accuracy. CS is an endocrine-metabolic disorder caused by hypercorticism, which is characterized by the absence of ...
Hayashi, Lilian Fukusima, Kater, Claudio Elias, Nakamura, Odete H, Noguti, Keiko O, Vieira, José Gilberto Henriques   +4 more
core   +3 more sources

Management of post‐implant fibrous dysplasia in the maxilla: A case study

Clinical Advances in Periodontics, EarlyView.
Abstract Background Fibrous dysplasia is generally rare, and even rarer in older adults. Special care is needed when altering the alveolar bone in these cases, especially if an implant is involved. This case study highlights such a scenario. Methods This case study details the experience of a 63‐year‐old African American female who presented with a ...
Yousef Taha Y. Amrou, Anass M. Koleilat, Abdusalam E. Alrmali, Felipe Nor, Hom‐Lay Wang   +4 more
wiley   +1 more source

Robert Milton Zollinger, M.D., teacher, surgeon, soldier, and farmer. [PDF]

, 2011
From Humble roots, Dr. Robert Milton Zollinger worked his way to a position in history among the giants of American surgery. He was born on September 4, 1903, in the central Ohio town of Millersport, the son of Elmira and William Zollinger.
Chory, B.S., Fiona M., Maxwell, IV, MD, Pinckney J., Yeo, MD, Charles J.   +2 more
core   +1 more source