Results 131 to 140 of about 7,299,987 (302)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
, 2014 In diagnostic studies, both sensitivity and specificity depend on cut-off point and they are well-known measures for diagnostic accuracy. The diagnostic cut-off point is mostly unknown and needs to be determined by some optimization criteria out of which
Yin, Jingjing, Tian, Lili
core +1 more source
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Cut-throat island point harbour
cut v(Hamilton Inlet) ...2 cables westward of Cut-throat error point [lies] Cut-throat point... Cut-throat harbour is entered about half a mile westward of the...island.
core
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Non-perturbative aspects of entanglement structures in $$T\overline{T }$$ -deformed CFTs
Journal of High Energy PhysicsTurning on the $$T\overline{T }$$ -deformation in a two-dimensional CFT provides a unique window to study explicitly how non-local features arise in the UV as a result of the deformation.
Wen-Xin Lai, Huajia Wang, Yongjiang Xu
doaj +1 more source
Cut-off point of mature oocyte for routine clinical application of rescue IVM: a retrospective cohort study. [PDF]
J Ovarian Res, 2023 Wei J +5 more
europepmc +1 more source
A Study on the Optimal Cut-off Point in the Cut-off Sampling Method
Korean Journal of Applied Statistics, 2014 Sang Eun Lee, Min Ji Cho, Key-Il Shin
openaire +2 more sources