Results 21 to 30 of about 748,340 (348)

The αMSH-Dependent PI3K Pathway Supports Energy Metabolism, via Glucose Uptake, in Melanoma Cells

Cells, 2023
Stimulation of melanocytes and murine melanoma cells with αMSH plus the PI3K inhibitor LY294002 resulted in ROS increase, oxidative DNA damage, and pigment retention.
Giorgia Cardinali, Daniela Kovacs, Sarah Mosca, Barbara Bellei, Enrica Flori, Aldo Morrone, Anna Maria Mileo, Vittoria Maresca   +7 more
doaj   +1 more source

Clinical and histopathological spectrum of delayed adverse cutaneous reactions following COVID‐19 vaccination

Journal of cutaneous pathology, 2021
As more people become vaccinated against the SARS‐CoV‐2 virus, reports of delayed cutaneous hypersensitivity reactions are beginning to emerge.
Valerie Larson, Roy Seidenberg, A. Caplan, N. Brinster, Shane A Meehan, Randie H. Kim   +5 more
semanticscholar   +1 more source

Re-biopsy of partially sampled thin melanoma impacts sentinel lymph node sampling as well as surgical margins

Melanoma Management, 2019
Aim: To assess the impact of re-biopsy on partially sampled melanoma in situ (MIS), atypical melanocytic proliferation (AMP) and thin invasive melanoma.
Evan S Weitman, Matthew C Perez, Daniel Lee, Youngchul Kim, William Fulp, Vernon K Sondak, Amod A Sarnaik, Ricardo J Gonzalez, Carl W Cruse, Jane L Messina, Jonathan S Zager   +10 more
doaj   +1 more source

Single-cell analysis reveals differences among iNKT cells colonizing peripheral organs and identifies Klf2 as a key gene for iNKT emigration

Cell Discovery, 2022
Invariant natural killer T cell (iNKT) subsets are differentially distributed in various immune organs. However, it remains unclear whether iNKT cells exhibit phenotypical and functional differences in different peripheral organs and how thymic iNKT ...
Jie Wang, Ian Loveless, Indra Adrianto, Tingting Liu, Kalpana Subedi, Xiaojun Wu, Md Moazzem Hossain, Eric Sebzda, Li Zhou, Qing-Sheng Mi   +9 more
doaj   +1 more source

PD‐1 Blockade with Cemiplimab in Advanced Cutaneous Squamous‐Cell Carcinoma

New England Journal of Medicine, 2018
Background No systemic therapies have been approved for the treatment of advanced cutaneous squamous‐cell carcinoma. This cancer may be responsive to immune therapy, because the mutation burden of the tumor is high and the disease risk is strongly ...
M. Migden, D. Rischin, C. Schmults, A. Guminski, A. Hauschild, K. Lewis, C. Chung, L. Hernandez-Aya, A. Lim, A. Chang, G. Rabinowits, A. Thai, L. Dunn, B. Hughes, N. Khushalani, B. Modi, D. Schadendorf, Bo Gao, F. Seebach, Siyu Li, Jingjin Li, M. Mathias, J. Booth, K. Mohan, E. Stankevich, H. Babiker, I. Braña, M. Gil-Martin, J. Homsi, M. Johnson, V. Moreno, J. Niu, T. Owonikoko, K. Papadopoulos, G. Yancopoulos, I. Lowy, M. Fury   +36 more
semanticscholar   +1 more source

Cutaneous signs in COVID‐19 patients: A review

Dermatologic Therapy, 2020
Coronavirus disease (COVID‐19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) primarily affects the epithelium of the airways.
U. Wollina, A. Karadağ, C. Rowland-Payne, A. Chiriac, T. Lotti   +4 more
semanticscholar   +1 more source

The Cutaneous Microcirculation [PDF]

Journal of Investigative Dermatology Symposium Proceedings, 2000
The cutaneous microcirculation is organized as two horizontal plexuses. One is situated 1-1.5 mm below the skin surface and the other is at the dermal-subcutaneous junction. Ascending arterioles and descending venules are paired as they connect the two plexuses.
openaire   +3 more sources

Efficacy and safety of topical treatments for seborrheic keratoses: a systematic review

Journal of Dermatological Treatment, 2023
Seborrheic keratoses (SKs) are benign epidermal neoplasms presenting as waxy, brown to black papules and plaques. Patients often seek removal for cosmetic reasons or irritation. The objective of this systematic review is to assess the efficacy and safety
Nicole Natarelli, Amanda Krenitsky, Kerry Hennessy, Sarah Moore, James Grichnik   +4 more
doaj   +1 more source

CDIP1-BAP31 Complex Transduces Apoptotic Signals from Endoplasmic Reticulum to Mitochondria under Endoplasmic Reticulum Stress

Cell Reports, 2013
Resolved endoplasmic reticulum (ER) stress response is essential for intracellular homeostatic balance, but unsettled ER stress can lead to apoptosis.
Takushi Namba, Fang Tian, Kiki Chu, So-Young Hwang, Kyoung Wan Yoon, Sanguine Byun, Masatsugu Hiraki, Anna Mandinova, Sam W. Lee   +8 more
doaj   +1 more source

Cutaneous leishmaniasis mimicking cutaneous lymphoma

IDCases, 2019
Cutaneous leishmaniasis (CL) is caused by protozoa of Leishmania genus that are transmitted to humans through the bite of sand flies (Lutzomyia and Phlebotomus). The infection is classically manifested as multiple or single ulcers affecting cutaneous and/or mucosal areas of the body.
Thalita dos Santos Bastos, Fernanda do Nascimento Rodrigues, Nathalia Gabay Pereira, Carla Andréa Avelar Pires, Amanda Gabay Moreira, Julie Marie Costa Sena, Jéssica Rayanne Corrêa da Silva, Caio César Chaves Costa, Evelyn de Paiva Faustino, Maria Amélia Lopes dos Santos   +9 more
openaire   +4 more sources