Results 21 to 30 of about 1,185,716 (346)

A Practical Approach to the Diagnosis of Lymphedema: a Narrative Review

Dermatology Practical & Conceptual, 2023
Introduction: Lymphedema often presents as progressive, unremitting swelling and skin changes that are extremely distressing to patients. Hereditary lymphedema (HL) constitutes a type of primary lymphedema that is passed down through generations ...
Lauren Banner, Alexa Cohen, Viral Patel, Neda Nikbakht   +3 more
doaj   +1 more source

miRNA- and cytokine-associated extracellular vesicles mediate squamous cell carcinomas

Journal of Extracellular Vesicles, 2020
Exosomes, or small extracellular vesicles (sEVs), serve as intercellular messengers with key roles in normal and pathological processes. Our previous work had demonstrated that Dsg2 expression in squamous cell carcinoma (SCC) cells enhanced both sEV ...
Joseph P. Flemming, Brianna L. Hill, Mohammed W. Haque, Jessica Raad, Claudine S. Bonder, Larry A. Harshyne, Ulrich Rodeck, Adam Luginbuhl, James K. Wahl, Kenneth Y. Tsai, Peter J. Wermuth, Andrew M. Overmiller, Mỹ G. Mahoney   +12 more
doaj   +1 more source

Recalcitrant Cutaneous Mastocytosis Treated With Genetically Informed Targeted Therapy: A Case Report

International Journal of Dermatology and Venerology, 2023
Introduction:. Mastocytosis, a clonal proliferation of mast cells commonly involving the skin and bone marrow, has a varied clinical presentation ranging from cutaneous lesions to systemic disease.
Laura Gleason, Volkan Tekmen, Alexa Cohen, Safiyyah Bhatti, Burcu Beksac, Jisun Cha, Pierluigi Porcu, Neda Nikbakht   +7 more
doaj   +1 more source

Disseminated cutaneous gout: a rare manifestation of a common disease [PDF]

, 2020
Disseminated cutaneous gout is a rare atypical cutaneous manifestation of gout in which widespread dermal and subcutaneous tophi develop at extra-articular body sites.
Adler, Brandon L, Crew, Ashley, DeClerck, Brittney, Guzman, Ruben, Peng, David   +4 more
core  

Unusual clinical presentation of cutaneous leishmaniasis in a patient with corticosteroid‐induced immunosuppression

Clinical Case Reports, 2021
Clinicians should always consider rare, atypical, and opportunistic infections in patients undergoing long‐term systemic corticosteroid therapy. Diagnosis needs further evaluations and special consideration.
Maryam Mahdavi, Reihaneh Aryan, Yalda Nahidi, Mehrdad Teimoorian, Vahid Mashayekhi   +4 more
doaj   +1 more source

PD‐1 Blockade with Cemiplimab in Advanced Cutaneous Squamous‐Cell Carcinoma

New England Journal of Medicine, 2018
Background No systemic therapies have been approved for the treatment of advanced cutaneous squamous‐cell carcinoma. This cancer may be responsive to immune therapy, because the mutation burden of the tumor is high and the disease risk is strongly ...
M. Migden, D. Rischin, C. Schmults, A. Guminski, A. Hauschild, K. Lewis, C. Chung, L. Hernandez-Aya, A. Lim, A. Chang, G. Rabinowits, A. Thai, L. Dunn, B. Hughes, N. Khushalani, B. Modi, D. Schadendorf, Bo Gao, F. Seebach, Siyu Li, Jingjin Li, M. Mathias, J. Booth, K. Mohan, E. Stankevich, H. Babiker, I. Braña, M. Gil-Martin, J. Homsi, M. Johnson, V. Moreno, J. Niu, T. Owonikoko, K. Papadopoulos, G. Yancopoulos, I. Lowy, M. Fury   +36 more
semanticscholar   +1 more source

Recurrent Cutaneous Tuberculosis in an Immunocompetent 7-Year-Old Male [PDF]

, 2018
Cutaneous tuberculosis (TB) makes up a small proportion of the 10.4 million cases around the world. Although it is more commonly found in the developing world, cutaneous TB is rarely reported in the developed countries.
Austin, Dena, Galvis, Alvaro, Jaiswal, Vidyasagar, Nakamura, Craig, Pecson, Iris   +4 more
core   +2 more sources

CDIP1-BAP31 Complex Transduces Apoptotic Signals from Endoplasmic Reticulum to Mitochondria under Endoplasmic Reticulum Stress

Cell Reports, 2013
Resolved endoplasmic reticulum (ER) stress response is essential for intracellular homeostatic balance, but unsettled ER stress can lead to apoptosis.
Takushi Namba, Fang Tian, Kiki Chu, So-Young Hwang, Kyoung Wan Yoon, Sanguine Byun, Masatsugu Hiraki, Anna Mandinova, Sam W. Lee   +8 more
doaj   +1 more source

Genome-wide association meta-analyses combining multiple risk phenotypes provides insights into the genetic architecture of cutaneous melanoma susceptibility

Nature Genetics, 2020
Most genetic susceptibility to cutaneous melanoma remains to be discovered. Meta-analysis genome-wide association study (GWAS) of 36,760 cases of melanoma (67% newly genotyped) and 375,188 controls identified 54 significant (P 
M. Landi, D. Bishop, S. Macgregor, M. Machiela, A. Stratigos, P. Ghiorzo, M. Brossard, D. Calista, Jiyeon Choi, M. Fargnoli, Tongwu Zhang, M. Rodolfo, A. Trower, C. Menin, Jacobo Martinez, A. Hadjisavvas, Lei Song, I. Stefanaki, R. Scolyer, Rose Yang, A. Goldstein, M. Potrony, K. Kypreou, L. Pastorino, P. Queirolo, C. Pellegrini, L. Cattaneo, M. Zawistowski, P. Giménez-Xavier, Arantxa Rodriguez, L. Elefanti, S. Manoukian, L. Rivoltini, Blair H. Smith, M. Loizidou, L. Del Regno, D. Massi, M. Mandalà, K. Khosrotehrani, L. Akslen, C. Amos, P. A. Andresen, M. Avril, E. Azizi, H. Soyer, V. Bataille, B. Dalmasso, L. Bowdler, K. Burdon, W. Chen, V. Codd, J. Craig, T. Dębniak, M. Falchi, S. Fang, E. Friedman, Sara Simi, P. Galan, Z. García-Casado, E. Gillanders, S. Gordon, A. Green, N. Gruis, J. Hansson, M. Harland, J. Harris, P. Helsing, A. Henders, M. Hočevar, V. Höiom, D. Hunter, C. Ingvar, Rajiv Kumar, J. Lang, G. Lathrop, Jeffrey E. Lee, Xin Li, J. Lubiński, R. MacKie, M. Malt, J. Malvehy, K. McAloney, H. Mohamdi, A. Molven, E. Moses, R. Neale, S. Novaković, D. Nyholt, H. Olsson, N. Orr, L. Fritsche, J. Puig-Butillé, A. Qureshi, G. Radford-Smith, J. Randerson-Moor, C. Requena, C. Rowe, N. Samani, Marianna Sanna, D. Schadendorf, H. Schulze, L. Simms, M. Smithers, F. Song, A. Swerdlow, N. van der Stoep, N. Kukutsch, A. Visconti, L. Wallace, S. Ward, L. Wheeler, R. Sturm, A. Hutchinson, K. Jones, Michael J Malasky, A. Vogt, Weiyin Zhou, K. Pooley, D. Elder, Jiali Han, B. Hicks, N. Hayward, P. Kanetsky, C. Brummett, G. Montgomery, C. Olsen, C. Hayward, A. Dunning, N. Martin, E. Evangelou, G. Mann, G. Long, P. Pharoah, D. Easton, J. Barrett, A. Cust, G. Abecasis, D. Duffy, D. Whiteman, H. Gogas, A. De Nicolo, M. Tucker, J. Newton-Bishop, K. Peris, S. Chanock, F. Demenais, K. Brown, S. Puig, E. Nagore, Jianxin Shi, M. Iles, M. Law   +151 more
semanticscholar   +1 more source

Clinical and histopathological spectrum of delayed adverse cutaneous reactions following COVID‐19 vaccination

Journal of cutaneous pathology, 2021
As more people become vaccinated against the SARS‐CoV‐2 virus, reports of delayed cutaneous hypersensitivity reactions are beginning to emerge.
Valerie Larson, Roy Seidenberg, A. Caplan, N. Brinster, Shane A Meehan, Randie H. Kim   +5 more
semanticscholar   +1 more source