Results 81 to 90 of about 110,182 (337)

Epigenetics in diagnosis, prognostic assessment and treatment of cancer:An update [PDF]

open access: yes, 2014
Cancer cells contain multiple genetic and epigenetic changes. The relative specificity of many epigenetic changes for neoplastic cells has allowed the identification of diagnostic, prognostic and predictive biomarkers for a number of solid tumors and ...
Briasoulis, Evangelos   +4 more
core   +4 more sources

Merkel Cell Carcinoma: Evolving Therapeutics, Continued Challenges

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Merkel Cell Carcinoma (MCC) is a rare, aggressive neuroendocrine malignancy with rising incidence, influenced by ultraviolet (UV) radiation and Merkel cell polyomavirus (MCPyV). Methods This review summarizes recent advances in MCC management, based on an analysis of current literature, focusing on immune checkpoint inhibitors (ICIs)
Hunter A. Holley   +6 more
wiley   +1 more source

Canine lymphoma: a retrospective study (2009-2010) [PDF]

open access: yes, 2012
This study reviews the medical records of 56 dogs diagnosed with lymphoma based on the cytological and/or histological results between January 1, 2009 and December 31, 2010.
Daminet, Sylvie   +3 more
core   +1 more source

p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis. [PDF]

open access: yes, 2013
The role of apoptosis in melanoma pathogenesis and chemoresistance is poorly characterized. Mutations in TP53 occur infrequently, yet the TP53 apoptotic pathway is often abrogated.
Akslen   +143 more
core   +1 more source

Consensus on the Clinical Approach to Moderate-to-Severe Atopic Dermatitis in Spain: A Delphi Survey [PDF]

open access: yes, 2020
Background. The purpose of this study was to gather information on the current assessment and management of patients with moderate-to-severe AD in routine daily practice. Methods.
Armario Hita, José Carlos   +9 more
core   +3 more sources

Clinical and genetic features of multiple primary tumours cohorts with a renal cell carcinoma: Implications for molecular genetic investigations

open access: yesInternational Journal of Cancer, EarlyView.
What's New? Current knowledge of the genetic architecture underlying the development of renal cell carcinoma‐related multiple primary tumours is limited. The authors comprehensively analysed the results of exome/genome sequencing cohorts including 534 patients to better define genotype–phenotype correlations.
Huairen Zhang   +6 more
wiley   +1 more source

Association of extraintestinal manifestations of inflammatory bowel disease in a province of western Hungary with disease phenotype: Results of a 25-year follow-up study [PDF]

open access: yes, 2003
AIM: IBD is a systemic disease associated with a large number of extraintestinal manifestations (EIMs). Our aim was to determine the prevalence of EIMs in a large IBD cohort in Veszprem Province in a 25-year follow-up study.
Balogh, Zsuzsanna   +6 more
core   +1 more source

Cutaneous T cell lymphomas [PDF]

open access: yesBMJ, 1994
Mycosis fungoides and the Sezary syndrome, together known as the cutaneous T cell lymphomas,1,2 are low grade non-Hodgkin's lymphomas with a mature helper T cell phenotype and monoclonal rearrangements of the T cell receptor genes. They should not be confused with intermediate and high grade non -Hodgkin's lymphomas of T cell origin affecting the skin -
openaire   +3 more sources

Classic Hairy Cell Leukemia With MAP2K1 Mutation: Diagnosis and Targeted Therapy

open access: yes
American Journal of Hematology, EarlyView.
Andrea Duminuco   +5 more
wiley   +1 more source

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