Results 91 to 100 of about 369,066 (292)

Pigmented Fibroepithelioma of Pinkus in Pregnancy: Strengths and Limitations of Reflectance Confocal Microscopy, Line‐Field Optical Coherence Tomography and Line‐Field Optical Coherence Tomography Artificial Intelligence Tool

JEADV Clinical Practice, EarlyView.
ABSTRACT Pigmented fibroepithelioma of Pinkus (FeP), a rare fibroepithelial variant of basal cell carcinoma (BCC), is clinically and dermoscopically challenging to diagnose and may mimic melanoma as well as benign lesions, such as sebhorreic keratosis.
Lucia Finistauri Guacci, Raimondo Rossi, Francesca Svara, Andrea Ascione, Giulio Bortone, Alessia Scipione, Steven Paul Nisticò, Giovanni Pellacani, Flavia Persechino   +8 more
wiley   +1 more source

A randomised trial evaluating Bevacizumab as adjuvant therapy following resection of AJCC stage IIB, IIC and III cutaneous melanoma : an update [PDF]

, 2008
At present, there are no standard therapies for the adjuvant treatment of malignant melanoma. Patients with primary tumours with a high-Breslow thickness (stages IIB and IIC) or with resected loco-regional nodal disease (stage III) are at high risk of ...
Middleton, M. (Mark), Corrie, P, Middleton, M, Dunn, J., East, C, Lorigan, P; id_orcid, Hern, A., Biswas, S., Wrigley, J., Lorigan, P., Wrigley, J, Dunn, Janet A., Marshall, A. (Andrea), Corrie, P., East, C., Marshall, A.   +15 more
core   +1 more source

Cutaneous Rosai‐Dorfman Disease With MAP2K1 Mutation Treated With Encorafenib and Binimetinib

JEADV Clinical Practice, EarlyView.
ABSTRACT Rosai‐Dorfman disease (RDD) is a rare histiocytic disorder with unifocal to multisystemic involvement. Activating mutations in the MAPK/ERK pathway can occur in up to 50% of RDD cases. We report a case of cutaneous RDD (C‐RDD) with facial and truncal lesions harboring an activating MAP2K1 (MEK1) mutation that showed a complete response to a ...
Melike Ak, Reinhard Dummer, Egle Ramelyte   +2 more
wiley   +1 more source

Cutaneous melanoma in Latin America: a population-based descriptive study

Cadernos de Saúde Pública, 2011
Cutaneous melanoma incidences vary between geographic regions and are a health concern for Caucasians and for all ethnic populations. In Latin America, data from population-based cancer registries of cutaneous melanoma incidence rates have rarely been ...
Ana Maria Sortino-Rachou, Maria Paula Curado, Marianna de Camargo Cancela   +2 more
doaj   +1 more source

Cutaneous melanoma [PDF]

British Journal of Cancer, 2001
Négrier, S, Fervers, B, Bailly, C, Beckendorf, V, Cupissol, D, Doré, J F, Dorval, T, Garbay, J R, Vilmer, C   +8 more
openaire   +2 more sources

Genomic Classification of Cutaneous Melanoma

, 2015
We describe the landscape of genomic alterations in cutaneous melanomas through DNA, RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 patients.
강효진, 이준학, The Cancer Genome Atlas Network   +2 more
core  

p63 is an alternative p53 repressor in melanoma that confers chemoresistance and a poor prognosis [PDF]

, 2013
The role of apoptosis in melanoma pathogenesis and chemoresistance is poorly characterized. Mutations in TP53 occur infrequently, yet the TP53 apoptotic pathway is often abrogated.
Graf, M, Mesher, D, Francesca Moretti, Chiorino, G, A. Chikh, Costanzo, A, M. Graf, D. Bergamaschi, Leigh, IM, Cerio, R, Maria Scatolini, Chong, SLP, C. M. Proby, Anissa Chikh, Antonio Costanzo, Matin, RN, Moretti, F, COSTANZO, ANTONIO, Charlotte M. Proby, Valentina Senatore, C. A. Harwood, Senatore, V, I. M. Leigh, D. Mesher, Harwood, CA, Catherine A. Harwood, R. N. Matin, Stephanie Law Pak Chong, Paolo Sanza’, Rino Cerio, R. Cerio, Bergamaschi, D, David Mesher, P. Sanza', M. Scatolini, Irene M. Leigh, S. L. Pak, Rubeta N. Matin, Proby, CM, V. Senatore, Daniele Bergamaschi, F. Moretti, Chikh, A, Sanza', P, Scatolini, M, Giovanna Chiorino, G. Chiorino, Manuela Graf   +47 more
core   +1 more source

A case of cutaneous melanoma metastatic to the ciliary body and choroid with complete regression via systemic dual checkpoint inhibitor therapy

BMC Ophthalmology
Background Cutaneous melanoma is the leading cause of death from cutaneous malignancy and tends to metastasize lymphatically and hematogenously to the lung, liver, brain, and bone; it is a rare source of metastatic disease to the eye. Herein we provide a
Ansam I. Qaddoumi, William I. Evans, Matthew W. Wilson   +2 more
doaj   +1 more source

Proteases in cutaneous melanoma

Annals of Medicine, 1998
From a great number of studies there is clear evidence that several extracellular proteolytic enzymes play an important role in various tumour-related processes. This review focusses on proteases in cutaneous melanoma. The current knowledge on and insights into the involvement of proteases in tumour progression are based on in vitro studies, on animal ...
Ferrier, C.M., Muijen, G.N.P. van, Ruiter, D.J.   +2 more
openaire   +3 more sources

Malignancy without immortality? Cellular immortalization as a possible late event in melanoma progression [PDF]

, 2011
P>Cell senescence is a permanent growth arrest following extended proliferation. Cultured cancer cells including metastatic melanoma cells often appear immortal (proliferate indefinitely), while uncultured benign nevi (moles) show senescence markers ...
Marais, R., Marais, R, Bennett, DC, Julia K. Soo, Chow, J, Hill, L, Chow, J., Ross, ADM, W. Nicol Keith, MacKenzie Ross, A.D., Hossain, M., Bennett, D.C., Heung Chong, W, Hoare, S, Mehnaz Hossain, Soo, JK, Dorothy C. Bennett, Rebecca S. Collinson, Carla Milagre, Milagre, C., David M. Kallenberg, Lucy Hill, Collinson, RS, Mackenzie Ross, AD, Hill, L., Chong, WH, Richard Marais, Kallenberg, DM, Soo, J.K., Jade Chow, Keith, W.N., Hossain, M, Heung Chong, W., Hoare, S., Stacey Hoare, Kallenberg, D.M., Milagre, C, W. Heung Chong, Collinson, R.S., Keith, WN, Alastair D. MacKenzie Ross   +40 more
core   +1 more source