Results 151 to 160 of about 98,994 (359)

Comparative Outcomes of Fine Needle Aspiration and Core Needle Biopsy for Parotid Masses

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To compare the diagnostic accuracy and safety of ultrasound‐guided fine needle aspiration (FNA) versus core needle biopsy (CNB) for parotid masses. Study Design Retrospective cohort study. Setting Tertiary academic medical center, 2018 to 2023. Methods We reviewed 485 patients undergoing ultrasound‐guided parotid biopsy (426 FNAs and
Lisa Eleni Chionis Buhler, Andrew Prince, Nicholas Bunda, Kimberly Oslin, Joshua Smith, Michael Allevato, Emma Hershey, Steven B. Chinn, Mark E. P. Prince   +8 more
wiley   +1 more source

Avaliação da toxicidade e da atividade antitumoral de derivados n-alquil ésteres do ácido gálico, livres ou encapsulados em nanopartículas lipídicas sólidas, para o estudo do melanoma in vitro e in vivo [PDF]

, 2011
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2011As terapias farmacológicas utilizadas nos casos avançados de melanoma metastático maligno parecem ser ...
Cordova, Clarissa Amorim Silva de
core  

RNA‐binding protein RBMS1: A new target for cancer diagnosis and treatment

Precision Medical Sciences, EarlyView.
This schematic illustrates the diverse regulatory roles of RNA‐binding motif single‐stranded interacting protein 1 (RBMS1) across multiple human cancers. In breast cancer, RBMS1 stabilizes B4GALT1 mRNA to promote PD‐L1 glycosylation, modulating tumor immune escape and immunotherapy efficacy.
Xingda Run, Shiwei Jiang, Kun Xu, Yu Fan, Yanwen Chen, Ziao Liu, Zengli Miao, Wei Tian   +7 more
wiley   +1 more source

Type I interferon overactivation in sera of patients with anti‐MDA5‐positive dermatomyositis‐associated interstitial lung disease

Rheumatology &Autoimmunity, EarlyView.
Sera from patients with anti‐MDA5‐positive dermatomyositis‐associated interstitial lung disease (ILD) exhibit significantly higher type I interferon (IFN‐I) bioactivity and interferon‐stimulated gene‐inducing activity compared to anti‐ARS‐positive ILD and healthy controls.
Shohei Nakamura, Yasuhiro Katsumata, Yuko Okamoto, Masayoshi Harigai   +3 more
wiley   +1 more source

DNA Methylation Array Analysis Identifies Biological Subgroups of Cutaneous Melanoma and Reveals Extensive Differences with Benign Melanocytic Nevi

Diagnostics
Background/Objectives: Genetics and epigenetics play an important role in the pathogenesis of cutaneous melanoma. The majority of cases harbor mutations in genes associated with the MAPK signaling pathway, i.e., BRAF, NRAS, or NF1.
Simon Schwendinger, Wolfram Jaschke, Theresa Walder, Jürgen Hench, Verena Vogi, Stephan Frank, Per Hoffmann, Stefan Herms, Johannes Zschocke, Van Anh Nguyen, Matthias Schmuth, Emina Jukic   +11 more
doaj   +1 more source

Effect of oxygen and nanoparticles on human skin and colon cells exposed to synchrotron‐based X‐ray FLASH beams

Journal of Synchrotron Radiation, EarlyView.
Most cancer patients will be treated by radiotherapy, and recent findings suggest that delivering radiation at `FLASH' ultra‐high dose rates reduces damage to healthy tissues while still damaging the tumour. This project experimentally validates the reduced healthy tissue damage of FLASH radiotherapy on cells using synchrotron‐based beams, which will ...
Moshi Geso, Matthew Cameron, Tom Ffrench, Helen Forrester, Rod Lynch, Masao Nakayama, William Patterson, Wan Nordiana Rahman, Duncan Butler, Terrence J. Piva   +9 more
wiley   +1 more source

Prognostic value of BRAF mutations in localized cutaneous melanoma

, 2014
BACKGROUND: \ud BRAF mutations are frequent in melanoma but their prognostic significance remains unclear.\ud OBJECTIVE: \ud We sought to further evaluate the prognostic value of BRAF mutations in localized cutaneous melanoma.\ud METHODS: \ud We ...
Requena, Celia, Hacker, Elke, Guillen, Carlos, Hayward, Nicholas K, Nagore, Eduardo, Traves, Victor, Whiteman, David C   +6 more
core   +1 more source

Recurrence Patterns and Prognostic Factors in Sentinel Lymph Node‐Negative Melanoma in a Taiwanese Cohort With Predominant Acral Melanoma

The Journal of Dermatology, EarlyView.
ABSTRACT Cutaneous melanoma in Asian populations is characterized by a predominance of acral melanoma and distinct clinicopathologic features. Although sentinel lymph node biopsy (SLNB) is widely used for staging, a subset of SLN‐negative patients still develop recurrence, and evidence regarding recurrence patterns and prognostic factors in this group ...
Chih‐Yuan Chang, Cheng‐Yuan Li, Tien‐Hsiang Wang, Chi‐Han Tsai, Jai‐Sing Yang, Yu‐Jen Chiu   +5 more
wiley   +1 more source

Comparative Molecular Insights into Developmental and Behavioral Toxicity Induced by Octocrylene and Ethylhexyl Salicylate Exposure on Zebrafish

Integrative Zoology, EarlyView.
This study compared the ecological toxicity of organic ultraviolet filters, octocrylene (OC) and ethylhexyl salicylate (EHS), on zebrafish embryos and larvae. EHS exhibited higher acute toxicity, causing increased mortality, hypoactive behavior at 50 mg/L, and disruptions in lipid homeostasis, while OC primarily affected hypoxia response and ...
Xiaoyang Lu, Li Sun, Jiao Chen, Jing Wang, Miao Guan, Shixia Xu   +5 more
wiley   +1 more source

Frequent downregulation of Fas (CD95) expression and function in melanoma

, 2002
Membrane-bound Fas ligand (FasL, Apo-1L, CD95L) induces rapid apoptosis of Fas (CD95)-sensitive cells on interaction with Fas, and is an important effector molecule of cytolytic T lymphocytes (CTLs). Melanomas are immunogenic and induce the production of
French, L. E., Bullani, R. R., Rimoldi, D., Tschopp, J., Viard-Leveugle, I., Wehrli, P., Cerottini, J. C., Saurat, J. H.   +7 more
core   +1 more source