Results 171 to 180 of about 369,066 (292)

Depicting the Immunological Landscape of Basal Cell Carcinoma Subtypes

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Anti‐PD‐1 response has been associated with higher PD‐1 ligand (PD‐L1) expression levels in different cancer types. Cemiplimab, an anti‐PD‐1 antibody, has been shown to induce a response rate of 31% and 22% in patients with locally advanced basal cell carcinoma (BCC) and metastatic BCC respectively, who have progressed or are ...
Isabella Dommann, Gaetana Restivo, Isabel Kolm, Federica Sella, Patrick Turko, Phil F. Cheng, Mitchell Levesque, Corina Dommann‐Scherrer, Reinhard Dummer, Egle Ramelyte   +9 more
wiley   +1 more source

Transcriptomic Profiling of Cutaneous Melanoma Metastases Treated With Microwave Ablation-Pilot Study. [PDF]

Clin Transl Sci
Losol P, O'Driscoll D, Pulido AV, von Witzleben A, Boukas K, Sommerlad M, Ottensmeier C, Ardern-Jones MR.   +7 more
europepmc   +1 more source

Diagnostic Utility of PRAME Immunohistochemistry for Distinguishing Acral Melanoma From Acral Melanocytic Nevi

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Introduction Preferentially expressed antigen in melanoma (PRAME) immunohistochemistry helps distinguish non‐acral melanocytic lesions, but few studies have addressed its value in acral lesions. We aimed to identify an optimal PRAME cut‐off score to differentiate acral melanoma (AM) from acral melanocytic nevi (AMN).
Kritsada Phatcharamaneepakorn, Panitta Sitthinamsuwan, Penvadee Pattanaprichakul, Manasmon Chairatchaneeboon, Nutcha Yodrabum   +4 more
wiley   +1 more source

MITF Is an Essential and Functionally Multifaceted Transcription Factor in Cutaneous Melanoma. [PDF]

Cancers (Basel)
Ondrušová L, Kreisingerová K, Vachtenheim J.   +2 more
europepmc   +1 more source

Eruptive Acral Melanocytic Lesions Associated With Capecitabine

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Eruptive nevi and lentigines have been reported to occur in the setting of immunosuppression, which may be medication‐induced. The associated histopathologic findings have not been well described in the literature. Herein, we report the case of a woman in her 60s who had been receiving chemotherapy treatment with capecitabine, a prodrug of 5 ...
Madison Smith, Annie Jin, Jonathan A. Miles, Rosalie Elenitsas, Danielle M. DeHoratius, Emily Y. Chu   +5 more
wiley   +1 more source

Microwave therapy for the treatment of cutaneous melanoma metastases - A pilot study. [PDF]

J Eur Acad Dermatol Venereol
O'Driscoll D, Losol P, Pulido AV, von Witzleben A, Boukas K, Sommerlad M, Ottensmeier C, Ardern-Jones MR.   +7 more
europepmc   +1 more source

A comparative analysis of clinical and sonographic features: cutaneous melanoma and melanocytic nevi. [PDF]

Transl Cancer Res
Ye W, Wang Y, Liu H, Jiang Y, Wang X, Qiu L, Tang Y.   +6 more
europepmc   +1 more source

Utility of IL‐18 Immunohistochemistry in Distinguishing Dermatomyositis and Lupus Erythematosus in Skin Biopsies

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Distinction of dermatomyositis (DM) and cutaneous lupus erythematosus (LE) in skin biopsies is often difficult due to significant histopathologic overlap. Prior transcriptional analysis has identified upregulation of IL‐18 in DM compared with LE.
Steven M. Hrycaj, Joseph S. Durgin, Johann E. Gudjonsson, J. Michelle Kahlenberg, Gaidaa R. Majari, Carole Bitar, Catherine G. Chung, Rosalynn M. Nazarian, May P. Chan   +8 more
wiley   +1 more source

Correction: Suppression of Spry1 reduces HIF1α‑dependent glycolysis and impairs angiogenesis in BRAF‑mutant cutaneous melanoma. [PDF]

J Exp Clin Cancer Res
Montico B, Giurato G, Guerrieri R, Colizzi F, Salvati A, Nassa G, Lamberti J, Memoli D, Sabatelli P, Comelli M, Bellazzo A, Fejza A, Camicia L, Baboci L, Bo MD, Covre A, Nyman TA, Weisz A, Steffan A, Maio M, Sigalotti L, Mongiat M, Andreuzzi E, Fratta E.   +23 more
europepmc   +1 more source

Disseminated Xanthogranuloma Harboring a GAB2::BRAF Fusion and MITF Pathogenic Variant Successfully Treated With Cobimetinib: A Rare Case Report

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Several activating mutations and gene fusions involving the mitogen‐activated protein kinase (MAPK) pathway have appeared in the literature regarding histiocytic neoplasms. We identified a GAB2::BRAF fusion in a cutaneous lesion of a 36‐year‐old male who developed central diabetes insipidus and reddish‐pink grouped papules on the bilateral ...
Pauline C. Xu, Allison M. Cushman‐Vokoun, Christopher R. D’Angelo, Dinesh Pradhan   +3 more
wiley   +1 more source