Background and Purpose The CKLF‐like MARVEL transmembrane domain containing superfamily (CMTM) has an important role in tumour immunity. The role of CMTM8 in tumour immune microenvironment (TIME) remains unknown. The aim was to investigate the relationship between CMTM8 and antitumour immunity. Experimental Approach Lentiviral system was established to
Fanglin Li +14 more
wiley +1 more source
RASD2 Drives Renal Clear Cell Carcinoma Progression via RAF1 (Ser338) Phosphorylation
RASD2 drives clear cell renal cell carcinoma (ccRCC) progression by physically interacting with RAF1 to induce its Ser338 phosphorylation, which subsequently activates the P38/ERK–MAPK signaling pathway to promote malignant tumor phenotypes and poor prognosis.
Jingxuan Yu +10 more
wiley +1 more source
T-Cell Stimulation by Melanoma RNA-Pulsed Dendritic Cells
In situations where well-established approaches such as surgery, radiation therapy and chemotherapy fail to help cancer patients, immunotherapy has the potential to be an effective alternative.
Javorovic, Miran
core
MAPK Inhibitor‐Tolerant Persister Cells in Melanoma: Mechanisms and Therapeutic Vulnerabilities
Melanoma response to MAPK inhibition progresses from drug‐sensitive cells to drug‐tolerant persister states, which enable survival through adaptive signaling, metabolic rewiring, and phenotypic plasticity. These persister cells serve as an intermediate reservoir from which resistant tumors ultimately emerge. ABSTRACT Though major advancements have been
Bhoomi Shah +3 more
wiley +1 more source
After a Decade of Therapy Revolution in Cutaneous Melanoma-Perspectives on Emerging Treatment Strategies. [PDF]
Wohlfeil SA, Utikal JS.
europepmc +1 more source
Association between Patient’s Basic Characteristic and Clark Level in Cutaneous Malignant Melanoma
Egie Rahmalaelani +2 more
openalex +2 more sources
Divergent Cellular Differentiation Pathways during the Invasive Stage of Cutaneous Malignant Melanoma Progression [PDF]
Jon A. Reed +2 more
openalex +1 more source
Cutaneous Melanoma in a Rabbit With Multiple Metastatic Lesions: A Case Report. [PDF]
Rostami A +5 more
europepmc +1 more source
RE: "RELIABILITY OF REPORTED SUNBURN HISTORY IN A CASE-CONTROL STUDY OF CUTANEOUS MALIGNANT MELANOMA" [PDF]
B. H. Fox
openalex +1 more source

