Results 251 to 260 of about 369,066 (292)
Some of the next articles are maybe not open access.
Metastasectomy in cutaneous melanoma
European Journal of Surgical Oncology (EJSO), 2017Metastasectomy remains the only treatment in malignant melanoma to offer complete pathologic response within a few days of in-hospital stay. It has been historically associated with the highest survival rates in the literature reported for patients of this stage.
K, Lasithiotakis, O, Zoras
openaire +2 more sources
Seminars in Cancer Biology, 2000
Members of some kindreds have a hereditary predisposition for development of cutaneous melanoma. Cytogenetic and linkage studies implicated chromosomes 1p and 9p as possible locations for genetic alterations predisposing for melanoma. Germline mutations in the CDKN2A gene on chromosome 9p21 have been identified in hereditary melanoma, but are present ...
A, Platz, U, Ringborg, J, Hansson
openaire +2 more sources
Members of some kindreds have a hereditary predisposition for development of cutaneous melanoma. Cytogenetic and linkage studies implicated chromosomes 1p and 9p as possible locations for genetic alterations predisposing for melanoma. Germline mutations in the CDKN2A gene on chromosome 9p21 have been identified in hereditary melanoma, but are present ...
A, Platz, U, Ringborg, J, Hansson
openaire +2 more sources
Prevention of Cutaneous Melanoma
2019The disease burden associated with melanoma continues to be a significant public health problem. The main modifiable risk factor for cutaneous melanoma is exposure to ultraviolet radiation, whether from the sun or artificial sources such as tanning sunbeds.
Sinclair, Craig +3 more
openaire +2 more sources
Melanoma Research, 1995
Family history is an important risk factor for cutaneous malignant melanoma. We evaluated the clinical characteristics of patients with cutaneous familial melanoma. A chart review was conducted, including all patients who presented to Massachusetts General Hospital Pigmented Lesion Clinic over an 8-year period.
L C, Lucchina +3 more
openaire +2 more sources
Family history is an important risk factor for cutaneous malignant melanoma. We evaluated the clinical characteristics of patients with cutaneous familial melanoma. A chart review was conducted, including all patients who presented to Massachusetts General Hospital Pigmented Lesion Clinic over an 8-year period.
L C, Lucchina +3 more
openaire +2 more sources
Epigenetics of Cutaneous Melanoma
Advances in Dermatology, 2008Tumorigenesis is traditionally thought to be caused by the imbalance between oncogenes and tumor-suppressor genes. Epigenetics is a recently described phenomenon that uses an alternative mechanism to explain the transcriptional inactivation of tumor-suppressor genes predominantly by hypermethylation of the promoter regions.
Willmar D, Patino, Joseph, Susa
openaire +2 more sources
Seminars in Oncology Nursing, 1991
C UTANEOUS MALIGNANT melanoma (CMM) is a cancer that arises in the melanin-producing cells called melanocytes. It is one of the most easily detected cancers, as the patient usually presents with a skin lesion that is readily visible. Melanomas that are detected early are almost always curable by surgical excision.’ With this in mind, the importance of ...
C, Grin-Jorgenson, A W, Kopf, J C, Maize
openaire +4 more sources
C UTANEOUS MALIGNANT melanoma (CMM) is a cancer that arises in the melanin-producing cells called melanocytes. It is one of the most easily detected cancers, as the patient usually presents with a skin lesion that is readily visible. Melanomas that are detected early are almost always curable by surgical excision.’ With this in mind, the importance of ...
C, Grin-Jorgenson, A W, Kopf, J C, Maize
openaire +4 more sources
The Classification of Cutaneous Melanoma
Hematology/Oncology Clinics of North America, 2009Forty years ago, a clinical and histological classification scheme and prognostic factors were described for cutaneous melanoma. This scheme included the subtypes superficial spreading, nodular and lentigo maligna, and prognostic factors including tumor thickness, ulceration, and mitotic activity.
openaire +2 more sources
Screening for Cutaneous Melanoma
Surgical Oncology Clinics of North America, 2005Current data do not support widespread population-based screening for melanoma. While the incidence of melanoma is high, the overall mortality is low, and thus any potential benefit of screening the general population is hard to demonstrate. No randomized controlled trial showing reduction in mortality has ever been completed and, given the expense and
Julie R, Lange, Charles M, Balch
openaire +2 more sources
Advances in cutaneous melanoma
Clinical and Translational Oncology, 2012After several decades of slow progress in the field of melanoma, significant advances have been reported in recent years. These include a better understanding of the molecular biology of the tumour, a new staging classification system, insights into the patterns of relapse in early stage, and new drugs for the treatment of advanced disease.
Enrique, Espinosa +6 more
openaire +2 more sources
Epidemiology of Cutaneous Melanoma
Dermatologic Clinics, 1985Although intermittent intense solar exposure and genetic traits such as fair skin continue to be associated with the risk of developing cutaneous melanoma, these factors fail to account for much of the incidence. Suggestive evidence has increased speculation that viral agents, radiation, hormones, chemicals in the workplace, and dietary factors play ...
R A, Lew, H K, Koh, A J, Sober
openaire +2 more sources