Results 71 to 80 of about 84,355 (327)
Engineering antibodies with cancer‐associated binding sites
BMEMat, EarlyView.This review describes antibodies that perform direct/indirect roles in cancer treatment by binding to effective targets and discusses how antibodies kill tumors and modulate tumor microenvironment through these targets. The classification of expression systems for antibody production is summarized to guide appropriate selection based on different ...
Yinqi Tian +4 more
wiley +1 more source
Fatal Cutaneous γ/δ T-Cell Lymphoma with Central Nerve System Metastasis [PDF]
, 2011 Cutaneous γ/δ T-cell lymphoma is an extremely rare and highly aggressive tumor that is often resistant to treatment, such as polychemotherapy and radiotherapy.
Kim, Kwang Ho +5 more
core +2 more sources
BMEMat, EarlyView.This review highlights the complex roles of cellular senescence in cancer progression and suppression, discusses the mechanisms and regulatory pathways involved, and evaluates the efficacy of the “One‐Two punch” sequential treatment approach while addressing emerging challenges in this novel therapeutic strategy.
Qiuming Pan +12 more
wiley +1 more source
Primary cutaneous lymphoma of scalp in a child: a case report [PDF]
, 2017 Cutaneous lymphomas are a heterogenous group of lymphoproliferative disorders with involvement of skin and form a separate group under Non-Hodgkin’s lymphoma.
Lakshmi, A. Bhagya, Sri, K. Satya
core +2 more sources
Cancer Communications, EarlyView.Abstract Background Diffuse large B‐cell lymphoma (DLBCL) is the most common subtype of aggressive non‐Hodgkin's lymphoma with distinct clinical and molecular heterogeneity. DLBCL that arises in extranodal organs is particularly linked to poor prognosis. This study aimed to determine the clinical and molecular characteristics of extranodal involvement (
Si‐Yuan Chen +46 more
wiley +1 more source
Cutaneous T-cell lymphomas [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011 These are peripheral T-cell tumours, usually expressing CD4 along with other T-cell markers. The CD30 molecule is expressed in a histologically distinct subset (vide infra). Classification: The WHO identifies some well-defined clinicopathological entities with distinct clinical behaviour. Indolent forms include mycosis fungoides, primary cutaneous CD30
Antonio Cuneo, Gianluigi Castoldi
openaire +1 more source
Persistent varicella as the initial manifestation of systemic lymphoma [PDF]
, 2008 Varicella is a common benign childhood disease that often presents in adolescents and adults in a more severe form. We report a previously healthy 50-year-old man who developed multiple necrotic cutaneous ulcers associated with fever, asthenia and ...
Ferreira, M. +4 more
core
Paraneoplastic pemphigus: insight into the autoimmune pathogenesis, clinical features and therapy [PDF]
, 2017 Paraneoplastic pemphigus is a rare autoimmune skin disease that is always associated with a neoplasm. Usually, oral, skin, and mucosal lesions are the earliest manifestations shown by paraneoplastic pemphigus patients.
Andrea Ciofalo +21 more
core +2 more sources
Streamlining Vorinostat Synthesis: A Chemoenzymatic Continuous Flow Approach
European Journal of Organic Chemistry, EarlyView.A chemoenzymatic protocol for the synthesis of histone deacetylase inhibitor vorinostat has been established. Immobilized lipase from C. antarctica (imm‐CaLB) allowed the functionalization of suberanoyl acid 1 and further conversion to vorinostat via ion‐exchange resin treatment.
Francesca Annunziata +6 more
wiley +1 more source
Cutaneous T-cell lymphoma: neoplasm of T cells with helper activity [PDF]
, 1979 Berger Cl +4 more
openalex +3 more sources