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Cellular Identity Crisis: RD3 Loss Fuels Plasticity and Immune Silence in Progressive Neuroblastoma
Researchers discovered that therapy‐induced loss of RD3 protein in neuroblastoma triggers a dangerous shift: cancer cells become more stem‐like, invasive, and resistant to treatment while evading immune detection. RD3 loss suppresses antigen presentation and boosts immune checkpoints, creating an immune‐silent environment.
Poorvi Subramanian +7 more
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Triple‐negative breast cancer has a poor prognosis. Xanthatin directly targets and degrades CISD1, triggering ferroptosis through iron dysregulation. The concurrently activated mitophagy synergistically amplifies ferroptotic cell death. Xanthatin also demonstrates potent in vivo anti‐tumor efficacy with minimal toxicity, highlighting its therapeutic ...
Qinwen Liu +9 more
wiley +1 more source
A resonant frequency engineering strategy is proposed to modulate the sensibility of piezoresistive textile‐based tactile sensor. It achieves simultaneous detection of static pressure and dynamic vibrations across an unprecedented bandwidth of 5–600 Hz, surpassing human sensation, therefore enables rapid and precise braille recognition.
Xianhong Zheng +17 more
wiley +1 more source
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Sorghum cuticular waxes influence host plant selection by aphids
Planta, 2022Quantification of cuticular waxes coupled with insect bioassays and feeding behavior analysis demonstrate that long-chain C32 fatty alcohol impacts host plant selection by aphids. Cuticular waxes constitute the first point of contact between plants and their environment, and it also protect plants from external stresses.
Juan Betancurt Cardona +4 more
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Cuticular wax of Epilachna varivestis
Insect Biochemistry, 1984Abstract Cuticular lipids of larvae, pupae and adults of the Mexican bean beetle (Epilachna varivestis) have been examined using gravimetric and thin layer densitometric techniques. The effects of rearing on different hostplants and of rearing temperature on lipid composition were studied.
David A. Danehower, Jon Bordner
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Biosynthesis and secretion of plant cuticular wax
Progress in Lipid Research, 2003The cuticle covers the aerial portions of land plants. It consists of amorphous intracuticular wax embedded in cutin polymer, and epicuticular wax crystalloids that coat the outer plant surface and impart a whitish appearance. Cuticular wax is mainly composed of long-chain aliphatic compounds derived from very long chain fatty acids.
L, Kunst, A L, Samuels
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Cuticular waxes from potato (Solanum tuberosum) leaves
Phytochemistry, 2006The qualitative and quantitative compositions of leaf cuticular waxes from potato (Solanum tuberosum) varieties were studied. The principal components of the waxes were very long chain n-alkanes, 2-methylalkanes and 3-methylalkanes (3.1-4.6 microg cm(-2)), primary alcohols (0.3-0.7 microg cm(-2)), fatty acids (0.3-0.6 microg cm(-2)), and wax esters (0 ...
Beata M, Szafranek, Elzbieta E, Synak
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