Results 31 to 40 of about 241,686 (283)

The use of deforming broaching for enhancing the efficiency of cutter chisels [PDF]

open access: yes, 2020
Purpose. To determine the potential of deforming broaching for the improvement of efficiency of cutter chisels in the mining industry. Methodology. The study of the application of the technological process of deforming broaching was carried out
Nemyrovskyi, Ya B., Krivosheya, V. V., Sardak, S. E., Shepelenko, I. V. & Tsekhanov, Yu A.   +1 more
core  

Method for real-time prediction of cutter wear during shield tunnelling: A new wear rate index and MCNN-GRU

open access: yesMethodsX, 2023
Cutter wear is one of the key factors influencing construction efficiency during shield tunnelling. Prediction of cutter wear can improve construction efficiency by reducing the times of cutter inspections in engineering practice.
Nan Zhang, Lin-Shuang Zhao
doaj   +1 more source

Precision glasscutter [PDF]

open access: yes, 1974
Glass is positioned against preset stops; and glasscutter, which is permanently mounted in carrier support by cutter guide rails, is used to scribe glass at predetermined length.
Coombs, D. S.
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

THE INCREASE IN DRILLING DURABILITY OF TRICONE BITS

open access: yesИзвестия высших учебных заведений: Нефть и газ, 2018
The process of location error the bit in the chuck was verified experimentally and put into production by measuring the gap between the working surface of the limiting ring and the calibrating surface of the cutter to improve the accuracy of the bit ...
M. Ya. Habibullin   +2 more
doaj   +1 more source

Hole cutter [PDF]

open access: yes, 1975
An adjustable hole cutter is described for use in forming circular openings in workpieces. The hole cutter is characterized by a mount of a substantially planar configuration, positionable into a plane paralleling the working plane of a selected ...
Newby, D. T., Thornton, G. E.
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

A Method for Evaluating the Rock Breaking Efficiency of Cutters and Optimizing the PDC Cutter Profile—A Study of Igneous Rock Formations in Shunbei Oilfield

open access: yesEnergies, 2022
The Permian igneous rock in Shunbei Oilfield exhibits high rock strength, which results in a low rate of penetration (ROP) and shortens the cutter’s service life. It is necessary to analyze and evaluate the rock breaking effect of cutters.
Zhuoxin Dong   +6 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Rock Breaking Simulation and Optimization of PDC Bit for Jimsar Shale Formation

open access: yesShiyou jixie
Conventional planar-cutter PDC bit exhibits prominent problems in drilling, such as severe wear, frequent cutter breakage and short footage, resulting in low drilling efficiency and high cost. To improve the drilling speed and reduce the drilling cost in
Zang Chuanzhen
doaj   +1 more source

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