Results 71 to 80 of about 241,686 (283)

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Design and Fabrication of An Automated Glass Bottle Cutter for Reuse and Recycling Bottle Glass Products

Journal of Engineering Technology and Applied Physics
The glass bottle cutter has a substantial commercialisation potential, as present trends indicate a growing interest in repurposing waste materials.
Alya Amanina binti Mohd Ishak, Ainaa Maya Munira Ismail, Ahmad Idzwan Yusuf, Ab Aziz Bin Mohd Yusof   +3 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Microwave interferometer controls cutting depth of plastics [PDF]

, 1969
Microwave interferometer system controls the cutting of plastic materials to a prescribed depth. The interferometer is mounted on a carriage with a spindle and cutting tool.
Heisman, R. M., Iceland, W. F.
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

An Experimental Study on Milling Titanium Alloy with a Revolving Cycloid Milling Cutter

Applied Sciences, 2020
In this paper, a revolving cycloid milling cutter was designed with a larger effective cutting helix angle and rake angle than a ball end milling cutter of the same diameter.
Guangyue Wang, Xianli Liu, Tao Chen, Weijie Gao   +3 more
doaj   +1 more source

Tracking Chart 2006 Cutter & Buck, Philippines 310059424E [PDF]

, 2006
This document is part of a digital collection provided by the Martin P. Catherwood Library, ILR School, Cornell University, pertaining to the effects of globalization on the workplace worldwide.
Fair Labor Association
core   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Design and Experiment of Customized PDC Bit for Volcanic Rock in the Northwestern Margin of Junggar Basin

Shiyou jixie, 2017
In view of the challenges of volcanic rocks in Junggar Basin like complex lithology, poor drillability and thick layer, the mechanics evaluation experiment of the volcanic rock in northwestern margin of the Junggar Basin has been carried out.
Yang Hu, Wen Qianbin, Zhou Penggao, Xiong Xudong, Sun Weiguo, Yang Hong   +5 more
doaj  

The Story of the Open Access Cookie Cutter

, 2014
The idea of an open access cookie cutter, how it was created with help from Chip Wolfe at Embry-Riddle Aeronautical University, and a recipe to bake the perfect cookie. Perfect to serve at OA Week events! Want to print your own cookie cutter?
Wertzberger, Janelle
core