Results 81 to 90 of about 2,361,401 (358)

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Modelling High Speed Machining with the SPH Method [PDF]

, 2008
The purpose of this work is to evaluate the use of the Smoothed Particle Hydrodynamics (SPH) method within the framework of high speed cutting modelling. First, a 2D SPH based model is carried out using the LS-DYNA® software.
Chieragatti, Rémy, Espinosa, Christine, Lacome, Jean-Luc, Limido, Jérôme, Mabru, Catherine, Salaün, Michel   +5 more
core  

A review of recent perspectives on biomechanical risk factors associated with anterior cruciate ligament injury [PDF]

, 2014
There is considerable evidence to support a number of biomechanical risk factors associated with non-contact anterior cruciate ligament (ACL) injury. This paper aimed to review these biomechanical risk factors and highlight future directions relating to ...
Boden B. P., Chappell D. J., Cruz A., Dai B., Donnelly C. J., Ford K. R., Frank B., Gerwyn Hughes, Grasso R., Griffin L. Y., Grood E. S., Hakkinen K., Herzog W., Irvine L. B., Jacobs C. A., Janssen I., Kernozek T. W., Smith B. A., Stojanovic M. D.   +18 more
core   +2 more sources

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Engagement of people with lived experience of dementia advisory group and cross-cutting program: reflections on the first year

Research Involvement and Engagement, 2022
Plain English summary In this paper, we describe the development of the Canadian Consortium of Neurodegeneration in Aging (CCNA) Engagement of People with Lived Experience of Dementia (EPLED) cross-cutting program and the first year of the EPLED Advisory
Ellen Snowball, Rosette Fernandez Loughlin, Heather Eagleson, Karen Myers Barnett, Emily McLellan, Denis O’Connor, Catherine Kelly, Christine Thelker, Katherine S. McGilton, Jennifer Bethell   +9 more
doaj   +1 more source

A performance of 2 dimensional ultrasonic vibration assisted milling in cutting force reduction, on aluminium AL6061 [PDF]

, 2016
This paper were investigate a performance of 2 Dimensional Ultrasonic Vibration assisted Milling (UVAM) toward Aluminium Al 6061. The focus is to find the performance of reduction of cutting force compared to the conventional machining in the industries ...
Abd. Rahim, Erween, Hui, Ding, Ibrahim, Rasidi, Kai, Cheng, Rafai, Noor Hakim   +4 more
core  

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Optical flow versus retinal flow as sources of information for flight guidance [PDF]

The appropriate description is considered of visual information for flight guidance, optical flow vs. retinal flow. Most descriptions in the psychological literature are based on the optical flow.
Cutting, James E.
core   +1 more source

An experimental investigation of chatter effects on tool life [PDF]

, 2009
Tool wear is one of the most important considerations in machining operations as it affects surface quality and integrity, productivity and cost. The most commonly used model for tool life analysis is the one proposed by F.W.
Altintas Y., Armarego E. J., E Budak, Koenigsberger F., Kronenberg M., M Kayhan, Stephenson D. A., Taylor F. W., Tlusty J., Tlusty J., Tobias S. A., Trent E. M.   +11 more
core   +1 more source