Results 91 to 100 of about 918,916 (305)
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Molecular Oncology, EarlyView.Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Discrete element modelling of rock cutting
Computer Methods in Materials Science, 2007 The present paper presents modelling of rock cutting processes using the discrete element method. Numerical algorithm of the discrete element method employing cylindrical and spherical elements has been implemented and numerical simulation of rock cutting has been carried out.
openaire +1 more source
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Packing and Cutting Stone Blocks Based on the Nonlinear Programming of Tree Cases
ComputationTypically, dimension stones, commonly called stone blocks, are cut into multiple small cuboid stones so that multiple sculptures can be produced. To use the stone block as efficiently as possible, it is essential to pack these small cuboids in each stone
Taeyong Kim
doaj +1 more source
CSSI Element: Elements: Bringing Montage To Cutting Edge Science Environments.
, 2020 We describe the use of Montage to create all-sky astronomy maps compliant with the Hierarchical Progressive Survey (HiPS) sky-tesselation scheme. These maps support panning and zooming across the sky to progressively smaller scales, and are used widely for visualization in astronomy.
Berriman, Bruce, Good, John C.
openaire +1 more source
Вплив способу отримання заготовки та його технологічних параметрів на якісні показники породоруйнівних елементів доліт [PDF]
, 2015 Розглядається проблема дослідження впливу на якісні показники робочої частини бурових доліт способу отримання його породоруйнівних елементів. Досліджено породоруйнівні елементи, виготовлені об'ємним армуванням у нерухомі форми, відцентровим армуванням у
Шуляр, І. О.
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Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Tungsten wire/FeCrAlY matrix turbine blade fabrication study [PDF]
The objective was to establish a viable FRS monotape technology base to fabricate a complex, advanced turbine blade. All elements of monotape fabrication were addressed.
Fleck, J. N., Melnyk, P.
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Особенности синтеза структуры функционально-ориентированных технологических процессов комбинированной отделочной обработки осевых лезвийных инструментов [PDF]
, 2009 In the given work weare developing a general approach and method for the synthesis of the technological finishing processes of axial cutting tools. They are based on morphological and functional-oriented synthesis of the rational structure of operations.
Маджид, А. Д. +2 more
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