Results 61 to 70 of about 21,838 (295)
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
Neural Network Modeling of Cutting Force and Chip Thickness Ratio for Turning Aluminum Alloy 7075-T6
Al-Khawarizmi Engineering Journal, 2018 The turning process has various factors, which affecting machinability and should be investigated. These are surface roughness, tool life, power consumption, cutting temperature, machining force components, tool wear, and chip thickness ratio.
Mohanned Mohammed H. AL-Khafaji
doaj +1 more source
Chinese Journal of Mechanical Engineering, 2023 The current research on noncircular hobbing mainly focuses on the linkage model and motion realization. However, the intermittent cutting characteristics of hobbing would increase uncertainties in the manufacturing process.
Dazhu Li +3 more
doaj +1 more source
Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
FEBS Open Bio, EarlyView.Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Tool life prediction and management for an integrated tool selection system [PDF]
, 1996 In machining, it is often difficult to select appropriate tools (tool holder and insert), machining parameters (cutting speed, feed rate and depth of cut) and tool replacement times for all tools due to the wide variety of tooling options and the ...
Alamin, Bubakar B.
core
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Research of Prediction of Gear Milling Force based on FEM Simulation of Oblique Cutting
Jixie chuandong, 2016 Considering the milling force calculated by using mechanical model or milling finite element simulation is time- consuming and tedious,a prediction method of milling force based on the finite element simulation of oblique cutting is proposed.
Wang Lei, Zai Shouxiang, Cui Yanmei
doaj
Clinical Validation of Plasma p‐217tau in Neurological Diseases
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi +13 more
wiley +1 more source
EFFECT OF DISK ANGLE IN PERFORMANCE OF DISK HARROW AT DIFFERENT SPEEDS [PDF]
Mesopotamia Journal of Agriculture, 2011 The experiment was carried out at fields of college of agriculture and forestry, university of Mosul to study the effect of two disk angles for the offset disk harrow 15°, 20° and 20°, 25° for the front and rear gang respectively , and three forward ...
Mothana A. Noori
doaj +1 more source