Results 91 to 100 of about 388,520 (305)
SPRK: A Low-Cost Stewart Platform For Motion Study In Surgical Robotics
, 2017 To simulate body organ motion due to breathing, heart beats, or peristaltic movements, we designed a low-cost, miniaturized SPRK (Stewart Platform Research Kit) to translate and rotate phantom tissue.
Goldberg, Ken +3 more
core +1 more source
Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway
Molecular Oncology, EarlyView.Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed +10 more
wiley +1 more source
The interdependence of forces during continuous centerless grinding
Известия высших учебных заведений. Поволжский регион:Технические наукиBackground. A distinctive feature of the implementation of the centerless grinding method is the condition of power closure at the contact points of the treated surface and the elements of the technological system, compliance with which largely ...
P.V. Malinin +3 more
doaj +1 more source
Density-operator evolution: Complete positivity and the Keldysh real-time expansion
, 2019 We study the reduced time-evolution of open quantum systems by combining quantum-information and statistical field theory. Inspired by prior work [EPL 102, 60001 (2013) and Phys. Rev. Lett.
Reimer, V., Wegewijs, M. R.
core +1 more source
Design of a smart turning tool with application to in-process cutting force measurement in ultraprecision and micro cutting [PDF]
, 2014 In modern micromachining, there is a need to measure and monitor certain machining process parameters in process so as to detect tool wear in real time, to optimize the process parameters setup, and to render the machining process some level of smartness
Chen, X, Cheng, K, Wang, C
core +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Energy efficiency in discrete-manufacturing systems: insights, trends, and control strategies [PDF]
, 2019 Since the depletion of fossil energy sources, rising energy prices, and governmental regulation restrictions, the current manufacturing industry is shifting towards more efficient and sustainable systems.
Diaz Castañeda, Jenny Lorena +1 more
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Ultrasonic treatment with nickel electroplating combined with oxidation for developing γ-Al2O3 washcoat on Fe-Cr-Al substrate [PDF]
, 2012 Fe-Cr-Al is used as metallic support for catalytic converter due to its high thermal conductivity, lower heat capacity, high temperature and mechanical shock resistance. γ-Al2O3 is the most widely used material as washcoat which embedded on metallic
Firdianto, Ade
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source