Results 91 to 100 of about 1,483,890 (296)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Portrait of Rex Nan Kivell aged 30, London, 1930 [picture] /
, 1930 Title devised by catalgouer from inscription.; Inscriptions: "Fenwick Cutting London"--Below image; "Print 1975/3 Item 11805; RNK at age of 30 when he was collecting Australiana"--In ink and pencil on verso.; Condition: Faded, yellowing, silvering, tears.
Cutting, Fenwick.
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An investigation on the mechanics of nanometric cutting and the development of its test-bed [PDF]
, 2003 The mechanics of machining at a very small depth of cut (100 nm or less) is not well understood. The chip formation physics, cutting forces generation, resulting temperatures and the size effects significantly affect the efficiency of the process and ...
Cheng, K, Guo, XJ, Luo, X, Holt, R
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
The interdependence of forces during continuous centerless grinding
Известия высших учебных заведений. Поволжский регион:Технические наукиBackground. A distinctive feature of the implementation of the centerless grinding method is the condition of power closure at the contact points of the treated surface and the elements of the technological system, compliance with which largely ...
P.V. Malinin +3 more
doaj +1 more source
The Progress of Creative Pattern Cutting [PDF]
This paper documents the journey of several research initiatives, which focused upon creative pattern cutting. Instigated by a peer-reviewed, journal paper entitled, ‘Insufficient Allure: The Luxurious Art and Cost of Creative Pattern Cutting’ (Almond ...
Almond, Kevin, Power, Jess
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Investigating the CO2 laser cutting parameters of MDF wood composite material [PDF]
, 2011 Laser cutting of medium density fibreboard (MDF) is a complicated process and the selection of the process parameters combinations is essential to get the highest quality of the cut section.
Olabi, Abdul-Ghani +5 more
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
, 2003 Title from caption list supplied by the photographer, see file NLA04/564.; Inscriptions: Signed by the photographer in pencil on reverse; "14-19"--in pencil on reverse.; Part of the collection: A blood red noon, photography of the Brindabella & southern ...
Cutting, Jeff, 1945-
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Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source