Journal of Ophthalmology, 2018 An original technique for enucleation of the eyeball with advanced retinoblastoma using high-frequency electric welding of biological tissues (HFEWBT) was developed in SI “Filatov Institute of Eye Diseases and Tissue Therapy of NAMS of Ukraine” in 2013.
N.F. Bobrova +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Использование современных инструментальных материалов при механической обработке резанием износостойкого чугуна ИЧ210Х30Г3 [PDF]
, 2013 В работе приведены результаты экспериментального исследования механической обработки резанием заготовок из износостойкого чугуна с повышенной твердостью. Предлагается использовать современные инструментальные сплавы.
Дядюра, К. О., Юнак, А. С.
core
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Experiment on Conical Pick Cutting Rock Material Assisted with Front and Rear Water Jet
Advances in Materials Science and Engineering, 2015 Conical picks are one kind of cutting tools widely used in engineering machinery. In the process of rock breaking, the conical pick bears great cutting force and wear. To solve the problem, a new method, conical pick assisted with high pressure water jet,
Xiaohui Liu +3 more
doaj +1 more source
A rotary centrifugal machining of replaceable multi-faceted cutting tool inserts
Известия высших учебных заведений. Поволжский регион:Технические науки, 2021 Background. The object of the research is replaceable multi-faceted carbide tool inserts with rounded cutting edges to increase their strength. The subject of the research is the operation of centrifugal-rotary processing for rounding the cutting edges
A.V. Lipov, N.N. Nyrkov, V.A. Lipov
doaj +1 more source
Modeling of process of gear milling for definition of the intense deformed state in replaceable many-sided plates of a worm mill [PDF]
MATEC Web of Conferences, 2019 The tool equipment plays an important role in work of machine-building enterprises. One of the most important elements of equipment is the metal-cutting tool [1].
Artamonov E.V. +2 more
doaj +1 more source
Integration of dynamic behaviour variations in the stability lobes method: 3D lobes construction and application to thin-walled structure milling [PDF]
, 2006 Vibratory problems occurring during peripheral milling of thin-walled structures affect the quality of the fin- ished part and, to a lesser extent, the tool life and the spindle life.
Arnaud, Lionel +3 more
core +3 more sources
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Energy efficiency in discrete-manufacturing systems: insights, trends, and control strategies [PDF]
, 2019 Since the depletion of fossil energy sources, rising energy prices, and governmental regulation restrictions, the current manufacturing industry is shifting towards more efficient and sustainable systems.
Diaz Castañeda, Jenny Lorena +1 more
core +2 more sources