Results 51 to 60 of about 9,483,959 (401)
Reliability assessment of cutting tool life based on surrogate approximation methods [PDF]
, 2014 A novel reliability estimation approach to the cutting tools based on advanced approximation methods is proposed. Methods such as the stochastic response surface and surrogate modeling are tested, starting from a few sample points obtained through ...
Kolios, Athanasios +1 more
core +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Applied Sciences, 2019 Cutting regime parameters play an important role in determining the efficiency of the grinding process and the quality of the ground parts. In this study, the influences of the cutting parameters, including the cutting depth (ae), the feed rate (Fe) and ...
Ngoc-Pi Vu +7 more
doaj +1 more source
Research on Cutting Temperature of GH4169 Turning with Micro-Textured Tools
Applied Sciences, 2023 The GH4169 superalloy has the characteristics of high strength, strong thermal stability, large specific heat capacity, small thermal conductivity, etc., but it is also a typical hard-to-cut material.
Xinmin Feng +3 more
doaj +1 more source
Optimization of cut surface quality during CNC Plasma Arc Cutting process [PDF]
, 2016 Optimization of cut surface quality during CNC plasma-arc cutting (PAC) of mild steel plates is presented. Using design of experiments (DOE) the optimum process parameters are estimated.
Kechagias, John +3 more
core
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Meitan kexue jishu, 2023 Roadheaders play a vital role in enhancing coal mine production efficiency, but they also generate a significant amount of dust during high-intensity cutting.
Wendong ZHOU, Hetang WANG, Leilei SI
doaj +1 more source
Statistical analysis of the effect of machining parameters on fatigue life of aerospace grade aluminum alloy (AL 6082T6) [PDF]
, 2013 In this research work, aerospace grade aluminium alloy (Al 6082-T6) was analysed for the effect of cutting parameters on the fatigue life of the machined samples and optimization of cutting parameters for response factor.
Ahmed, Riaz +6 more
core
Surface microhardening studies on steels after high feed milling [PDF]
, 2018 The paper deals with the impact of high-speed machining production methods on the integrity of component surfaces. One has to point out that cutting conditions during machining have a significant impact on the final properties of surface and subsurface ...
Petrů, Jana +3 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source