Results 61 to 70 of about 5,220,601 (292)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Cutting parameters at needle-milling

Izvestiya MGTU MAMI, 2009
In article is open the questions wire brash, its specific and advantage in comparison with other ways of performance of operations of preparation of surfaces of preparations for anticorrosive covering of metal, welding by explosion etc. In article are consider еhe questions of the basic parameters of cutting at wire brash and on what they depend, and ...
V P Voronov, M I Sedykh
openaire   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Cutting test parameters determined via drilling depth and cutting thickness.

, 2021
Cutting test parameters determined via drilling depth and cutting thickness.
Xianguo Yan (11719431), Guoqiang Qin (7208924), Mengqi Zhang (1580830)   +2 more
core   +1 more source

Automatic Optimization System of Cutting Condition forDifferent Types of Machining Processes

Al-Khawarizmi Engineering Journal, 2009
This research aims at calculating the optimum cutting condition for various types of machining methods, assisted by computers, (the computer program in this research is designed to solve linear programs; the program is written in v. basic language).
Huda Hatem, Ali H. Kadhum
doaj  

Effect of cutting parameters on cutting force and surface quality in cutting of articular cartilage

Procedia CIRP, 2020
Abstract In this paper, we studied the influence of cutting parameters on cutting force and surface quality during resection of articular cartilage, which has not previously been investigated to any great extent. Triangular tooth shaver and porcine articular cartilage were used in this paper.
Xiaolin Pang, Yue Zhang, Chengyong Wang, Zhihua Chen, Na Tang, Bin Chen   +5 more
openaire   +1 more source

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Investigation of Cutting Tools and Working Conditions Effects when Cutting Ti-6al-4V using Vegetable Oil-Based Cutting Fluids [PDF]

, 2015
Power consumed in metal cutting is typically converted into heat near the cutting tool edge. Cutting fluids are then provided to a cutting zone in order to improve the tribological characteristics of machining processes and to dissipate the generated ...
Gariani, Salah, Shyha, Islam, Bhatti, M.
core   +1 more source

Investigation of Air Quality and Particle Emission During Wet Granite Edge Finishing on Machine Tool with Half-Beveled and Ogee Profile Tools

Journal of Manufacturing and Materials Processing
Granite wet edge finishing is widely adopted to improve surface durability and aesthetics while reducing dust dispersion compared to dry processes. However, even under flooded lubrication, fine particles (FP, 0.5–20 µm) and ultrafine particles (UFP,
Wael Mateur, Victor Songmene, Ali Bahloul, Mohamed Nejib Saidi, Jules Kouam   +4 more
doaj   +1 more source

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source