Results 71 to 80 of about 9,483,959 (401)
Design of a smart turning tool with application to in-process cutting force measurement in ultraprecision and micro cutting [PDF]
, 2014 In modern micromachining, there is a need to measure and monitor certain machining process parameters in process so as to detect tool wear in real time, to optimize the process parameters setup, and to render the machining process some level of smartness
Chen, X, Cheng, K, Wang, C
core +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Composite structures, 2019 The cutting tool geometry is strongly influencing damage induced during drilling of composite materials. The searching of new and optimum geometries reducing the damage on the laminates is still a challenge for the scientific community and industry. This
N. Feito +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Simulation of small-aperture deep hole drilling based on ABAQUS
Journal of Measurement Science and Instrumentation, 2015 This paper studies the influence of cutting parameters on deformation and residual stress of the workpiece with small-aperture deep holes in the process of drilling for the purpose of obtaining the variation law of the cutting force and residual stress ...
WANG Yi-nuo, CHEN Cong-jian
doaj
Finite Element Simulation of Bending Thin-Walled Parts and Optimization of Cutting Parameters
Metals, 2023 Aiming at the problems of large elastic deformation and low machining accuracy in cutting titanium alloy thin-walled parts, this paper establishes the finite element model of milling titanium alloy thin-walled parts, and simulates and analyses the ...
Ma Hailong +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Analysis of cutting parameters in point machining of parts with complex shape [PDF]
, 2018 This paper presents developed SW module in the postprocessor, which is designed to backward analysis of CAM milling toolpath. The module is designed to analyze multi-axis finishing machining of complex shape parts with milling cutters with a circular ...
Rybín J. +3 more
core
Effect of cutting parameters on cutting force and surface quality in cutting of articular cartilage
Procedia CIRP, 2020 Abstract In this paper, we studied the influence of cutting parameters on cutting force and surface quality during resection of articular cartilage, which has not previously been investigated to any great extent. Triangular tooth shaver and porcine articular cartilage were used in this paper.
Xiaolin Pang +5 more
openaire +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source