Results 111 to 120 of about 408,011 (339)

Evolutionary Cutting Planes

open access: yes, 2015
The Cutting Plane method is a simple and efficient method for optimizing convex functions in which subgradients are available. This paper proposes several methods for parallelizing it, in particular using a typically evolutionary method, and compares them experimentally in a well-conditioned and ill-conditioned settings.
Decock, Jérémie   +2 more
openaire   +1 more source

Cutting rectangles in the plane

open access: yesDiscrete Mathematics, 1982
AbstractLet F be a planar family of pairwise disjoint translates of a parallelogram. It is shown that if every four members of F are intersected by some straight line, then there is a straight line which intersects all but at most two members of F. If it is instead assumed that every two members of F are intersected by some line that is parallel to one
Katchalski, Meir, Lewis, Ted
openaire   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Proximal Analytic Center Cutting Plane Algorithms for Variational Inequalities and Nash Economic Equilibrium

open access: yesMathematics
In this study, we proposed proximal analytic center cutting plane algorithms for solving variational inequalities whose domains are normal regions. Our algorithms stop with a solution of the variational inequality after a finite number of iterations, or ...
Renying Zeng
doaj   +1 more source

Computer-aided design of bevel gear tooth surfaces [PDF]

open access: yes
This paper presents a computer-aided design procedure for generating bevel gears. The development is based on examining a perfectly plastic, cone-shaped gear blank rolling over a cutting tooth on a plane crown rack.
Coy, John J.   +2 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Research and Realization of Medical Volume Data Interactive Cutting

open access: yesJournal of Algorithms & Computational Technology, 2010
Medical image visualization is an important field of scientific computing visualization. Three-dimensional segmentation plays a very important role in three-dimensional reconstruction of human tissues and region of interest.
Wu Jian   +4 more
doaj   +1 more source

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