Results 91 to 100 of about 191,202 (337)

Calculation of principal stresses and their directions in selected cutting planes in rock drilling [PDF]

Acta Montanistica Slovaca, 2011
The paper is focused on the analysis of principal stress fields induced in the system of drilling tool-rock during the drilling process in immediate surroundings of their mutual contact. Various load conditions were analyzed, representing torque, loading
František Krepelka, Lucia Ivaničová, Milan Labaš, Jozef Futó   +3 more
doaj  

Correction and accuracy improvement of non-parallel shear zone model

MATEC Web of Conferences, 2018
When applying the non-parallel shear zone model to predict the cutting process parameters of carbon steel workpiece, it is found that there is a big error between the prediction results and the experimental values. And also, the former approach to obtain
Wang Yaoke, Kou Meng, Ding Wei, Ma Huan, Xiong Liangshan   +4 more
doaj   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Separating valid odd-cycle and odd-set inequalities for the multiple depot vehicle scheduling problem

EURO Journal on Computational Optimization, 2013
We consider the multicommodity network flow formulation of the multiple depot vehicle scheduling problem (MDVSP) and investigate several strategies within a branch-and-cut framework for solving the MDVSP.
Mounira Groiez, Guy Desaulniers, Ahmed Hadjar, Odile Marcotte   +3 more
doaj   +1 more source

Molecular dynamics simulation investigation of hot nanometric cutting of single crystal silicon [PDF]

, 2016
In this study, molecular dynamics (MD) simulation is employed to investigate mechanisms occurring during nanometric cutting process of single crystal silicon on different crystallographic planes under a wide range of workpiece temperatures (300-1500 K ...
Luo, Xichun, Zare Chavoshi, Saeed
core  

Efficient Algorithms for Moral Lineage Tracing

, 2017
Lineage tracing, the joint segmentation and tracking of living cells as they move and divide in a sequence of light microscopy images, is a challenging task. Jug et al.
Andres, Bjoern, Blasse, Corinna, Jug, Florian, Lange, Jan-Hendrik, Menze, Bjoern H., Myers, Eugene W., Rempfler, Markus   +6 more
core   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

A dual method for polar cuts in disjoint bilinear programming

Croatian Operational Research Review
As one branch of deterministic approaches to disjoint bilinear programming, cutting plane methods are renowned for its ability to systematically reduce the search space by adding cutting planes that are able to cut off regions deemed infeasible or ...
Xiaosong Ding, Jun Ma, Xi Chen, Chao Liu
doaj   +1 more source

Analysis and stiffness evaluation of a microparallel kinematic machine

Dyna, 2017
This study explores a scaled version of a 3-PRRR parallel configuration that can be used in micro-machining tasks. The study addresses a stiffness model of a micro-parallel kinematic machine (mPKM) by employing an approach involving kinematic and static ...
Ricardo Yáñez-Valdez
doaj   +1 more source

Disjunctive programs and sequences of cutting-planes / BEBR No. 576 [PDF]

Title page includes summary of paper.Includes bibliographical references (p. 13)
Blair, Charles Eugene
core