Results 71 to 80 of about 189,838 (273)
Analysis of the Technological Parameters of the Heat Exchanger in the Heating Pipe
MATEC Web of Conferences, 2017 The main purpose of this article is to analyze the selecting of technological parameters for the heat exchanger to improve the heat transfer and reduce the noise during operation in the heating pipe, which is used in the different systems of the planes ...
Knyazev Vladimir, Bubnov Gregory
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Cutting Plane and Frege Proofs
Information and Computation, 1995 The cutting plane refutation system CP for classical propositional calculus [see \textit{W. Cook}, \textit{C. R. Coullard} and \textit{Gy. Turan}, Discrete Appl. Math. 18, 25-38 (1987; Zbl 0625.90056)], initially coming from works in operation research, can be considered as an extension of resolution based on showing the non-existence of solutions for ...
openaire +2 more sources
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Efficient 3D data compression through parameterization of free-form surface patches [PDF]
, 2011 This paper presents a new method for 3D data compression based on parameterization of surface patches. The technique is applied to data that can be defined as single valued functions; this is the case for 3D patches obtained using standard 3D scanners ...
Osman, Abdulsslam +2 more
core
Multiple Cuts in the Analytic Center Cutting Plane Method
SIAM Journal on Optimization, 2000 Summary: We analyze the multiple cut generation scheme in the analytic center cutting plane method. We propose an optimal primal and dual updating direction when the cuts are central. The direction is optimal in the sense that it maximizes the product of the new dual slacks and of the new primal variables within the trust regions defined by Dikin's ...
Goffin, Jean-Louis, Vial, Jean-Philippe
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Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Experimental Parameters Influence the Observed Antimicrobial Response of Oak Wood (Quercus petraea)
Antibiotics, 2020 The present investigation aimed to utilize a direct wood disc diffusion method to study the influence of plane of cutting, cutting method, sterilization method, and origin of tree on the antimicrobial activity of wood material.
Muhammad Tanveer Munir +6 more
doaj +1 more source
The Analytic Center Cutting Plane Method with Semidefinite Cuts
SIAM Journal on Optimization, 2003 Summary: We analyze an analytic center cutting plane algorithm for convex feasibility problems with semidefinite cuts. The problem of interest seeks a feasible point in a bounded convex set, which contains a full-dimensional ball with radius \(\varepsilon
Oskoorouchi, Mohammad R. +1 more
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ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source