Results 81 to 90 of about 189,838 (273)

A Cutting Method with Updating Approximating Sets and its Combination with Other Algorithms

open access: yesИзвестия Иркутского государственного университета: Серия "Математика", 2014
For solving constrained minimization problem propose a cutting plane method which belongs to a class of cutting methods.The designed method uses an approximation of the epigraph of the objective function.
I.Ya. Zabotin, R.S. Yarullin
doaj  

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

open access: yesMolecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken   +7 more
wiley   +1 more source

Studying mechanism of anisotropic crack generation on C-, R-, A-, and M-planes of sapphire during ultra-precision orthogonal cutting using a visualized slip/fracture activation model

open access: yesNanotechnology and Precision Engineering
With the growing demand for the fabrication of microminiaturized components, a comprehensive understanding of material removal behavior during ultra-precision cutting has become increasingly significant.
Suk Bum Kwon, Sangkee Min
doaj   +1 more source

On the development of kink-bands: A case study in the Westasturian-Leonese Zone (Variscan belt, NW Spain)

open access: yesBSGF - Earth Sciences Bulletin, 2020
A field analysis of kink bands developed in slates from three areas (Grandas, Boal and Luarca areas) of the Westasturian-Leonese Zone (Iberian Variscan belt) is presented.
Aller Jesús   +2 more
doaj   +1 more source

A cutting plane algorithm for Modularity maximization with heuristics for separation problem [PDF]

open access: yes, 2013
The modularity proposed by Newman and Girvan is the most commonly used measure when the nodes of a graph are grouped into communities consisting of tightly connectednodes.
IZUNAGA Yoichi   +2 more
core  

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Mechanism of Water Inrush Induced by Gob Water Under Repeated Mining and Control Technology Based on Roof Cutting Pressure Relief

open access: yesApplied Sciences
To mitigate the threat posed by accumulated gob water to underlying coal seams during multi-seam mining, this study investigates the mechanism of water inrush induced by repeated mining and its control through roof cutting pressure relief.
Yongqiang Zhang   +5 more
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Calculation of principal stresses and their directions in selected cutting planes in rock drilling [PDF]

open access: yesActa Montanistica Slovaca, 2011
The paper is focused on the analysis of principal stress fields induced in the system of drilling tool-rock during the drilling process in immediate surroundings of their mutual contact. Various load conditions were analyzed, representing torque, loading
František Krepelka   +3 more
doaj  

Correction and accuracy improvement of non-parallel shear zone model

open access: yesMATEC Web of Conferences, 2018
When applying the non-parallel shear zone model to predict the cutting process parameters of carbon steel workpiece, it is found that there is a big error between the prediction results and the experimental values. And also, the former approach to obtain
Wang Yaoke   +4 more
doaj   +1 more source

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