Results 101 to 110 of about 718,654 (353)

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Thermocouple and Infrared Sensor-Based Measurement of Temperature Distribution in Metal Cutting

open access: yesSensors, 2015
In metal cutting, the magnitude of the temperature at the tool-chip interface is a function of the cutting parameters. This temperature directly affects production; therefore, increased research on the role of cutting temperatures can lead to improved ...
Abdil Kus   +4 more
doaj   +1 more source

Development of Thermomechanical Model for the Analysis of Effects of Friction and Cutting Speed on Temperature Distribution around AISI 316L During Orthogonal Machining [PDF]

open access: yes, 2017
In metal cutting,severe deformation takes place in the vicinity of the cutting edge of the high strain-rate and an increase in temperature is observed. Deformation behaviour of the work material in the primary and secondary zones is highly sensitive to ...
Abiola , Abatan   +3 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Simulation and Experimental Research on the Longitudinal–Torsional Ultrasonic Cutting Process Characteristics of Aramid Honeycomb Materials

open access: yesApplied Sciences
Aiming at the problems of large cutting force, easy honeycomb tearing, and deformation during the traditional cutting process of aramid honeycomb materials and an increase in cutting temperature during continuous processing, which may lead to vibration ...
Mingxing Zhang   +6 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Nonperturbative calculation of the shear viscosity in hot phi**4 theory in real time [PDF]

open access: yes, 1999
Starting from the Kubo formula we calculate the shear viscosity in hot phi**4 theory nonperturbatively by resumming ladders with a real-time version of the Bethe-Salpeter equation at finite temperature.
Heinz, Ulrich, Wang, Enke
core   +2 more sources

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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